Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= C55F2_1
(2001 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|25145656|ref|NP_741451.1| IMP cyclohydrolase (4I663) [Caenorh... 1334 0.0
gi|25145659|ref|NP_741452.1| IMP cyclohydrolase (67.4 kD) (4I663... 1204 0.0
gi|39595034|emb|CAE70902.1| Hypothetical protein CBG17698 [Caeno... 1199 0.0
gi|29570507|gb|AAL27233.2| Hypothetical protein C55F2.1a [Caenor... 850 0.0
gi|24649832|ref|NP_651305.1| CG11089-PA [Drosophila melanogaster... 679 0.0
gi|49250888|gb|AAH74584.1| Unknown (protein for MGC:69458) [Xeno... 676 0.0
gi|48675845|ref|NP_112276.2| 5-aminoimidazole-4-carboxamide ribo... 674 0.0
gi|1263196|gb|AAA97405.1| AICAR formyltransferase/IMP cyclohydro... 674 0.0
gi|28373618|pdb|1M9N|A Chain A, Crystal Structure Of The Homodim... 673 0.0
gi|45384004|ref|NP_990509.1| 5-aminoimidazole-4-carboxamide-ribo... 673 0.0
gi|20127454|ref|NP_004035.2| 5-aminoimidazole-4-carboxamide ribo... 672 0.0
gi|2541906|dbj|BAA22837.1| 5-aminoimidazole-4-carboxamide ribonu... 671 0.0
gi|37572276|gb|AAH39925.2| 5-aminoimidazole-4-carboxamide ribonu... 669 0.0
gi|27229048|ref|NP_080471.1| 5-aminoimidazole-4-carboxamide ribo... 668 0.0
gi|48734658|gb|AAH72321.1| Unknown (protein for IMAGE:6317471) [... 667 0.0
gi|14278285|pdb|1G8M|A Chain A, Crystal Structure Of Avian Atic,... 662 0.0
gi|31242553|ref|XP_321707.1| ENSANGP00000015783 [Anopheles gambi... 660 0.0
gi|34305305|gb|AAQ63487.1| 5-aminoimidazole-4-carboxamide ribonu... 651 0.0
gi|7498000|pir||T29605 hypothetical protein C55F2.1 - Caenorhabd... 645 0.0
gi|46439064|gb|EAK98386.1| hypothetical protein CaO19.492 [Candi... 643 0.0
gi|6323768|ref|NP_013839.1| Enzyme of 'de novo' purine biosynthe... 640 0.0
gi|50551513|ref|XP_503230.1| hypothetical protein [Yarrowia lipo... 640 0.0
gi|50311693|ref|XP_455873.1| unnamed protein product [Kluyveromy... 639 0.0
gi|49094280|ref|XP_408601.1| hypothetical protein AN4464.2 [Aspe... 636 0.0
gi|50260232|gb|EAL22891.1| hypothetical protein CNBA6600 [Crypto... 635 0.0
gi|37515243|gb|AAQ91905.1| Hypothetical protein C55F2.1c [Caenor... 635 0.0
gi|50284971|ref|XP_444914.1| unnamed protein product [Candida gl... 630 e-179
gi|12848590|dbj|BAB28011.1| unnamed protein product [Mus musculus] 628 e-178
gi|6323056|ref|NP_013128.1| Enzyme of 'de novo' purine biosynthe... 626 e-178
gi|50424841|ref|XP_461010.1| unnamed protein product [Debaryomyc... 626 e-178
gi|32422769|ref|XP_331828.1| hypothetical protein [Neurospora cr... 621 e-176
gi|46108174|ref|XP_381145.1| conserved hypothetical protein [Gib... 620 e-176
gi|45198731|ref|NP_985760.1| AFR213Cp [Eremothecium gossypii] >g... 610 e-173
gi|38104055|gb|EAA50676.1| hypothetical protein MG04435.4 [Magna... 608 e-172
gi|49068698|ref|XP_398638.1| hypothetical protein UM01023.1 [Ust... 606 e-172
gi|47230601|emb|CAF99794.1| unnamed protein product [Tetraodon n... 602 e-170
gi|19075527|ref|NP_588027.1| putative 5-aminoimidazole-4-carboxa... 601 e-170
gi|26345052|dbj|BAC36175.1| unnamed protein product [Mus musculus] 449 e-124
gi|16768972|gb|AAL28705.1| LD12501p [Drosophila melanogaster] 439 e-121
gi|11257038|pir||T43150 probable phosphoribosylaminoimidazolecar... 412 e-113
gi|26338005|dbj|BAC32688.1| unnamed protein product [Mus musculus] 406 e-112
gi|26369191|dbj|BAB26949.2| unnamed protein product [Mus musculus] 405 e-111
gi|29345928|ref|NP_809431.1| Bifunctional purine biosynthesis pr... 399 e-109
gi|15895710|ref|NP_349059.1| AICAR transformylase domain of PurH... 360 7e-98
gi|7507262|pir||T16819 hypothetical protein T06C10.1 - Caenorhab... 355 2e-96
gi|20092807|ref|NP_618882.1| phosphoribosylaminoimidazolecarboxa... 290 1e-76
gi|27262340|gb|AAN87451.1| phosphoribosylaminoimidazolecarboxami... 288 3e-76
gi|21227000|ref|NP_632922.1| formyltransferase phosphoribosylami... 284 6e-75
gi|48841015|ref|ZP_00297941.1| COG0138: AICAR transformylase/IMP... 280 7e-74
gi|27375692|ref|NP_767221.1| bifunctional purine biosynthesis pr... 280 7e-74
gi|16131836|ref|NP_418434.1| phosphoribosylaminoimidazolecarboxa... 277 8e-73
gi|15804597|ref|NP_290638.1| phosphoribosylaminoimidazolecarboxa... 276 1e-72
gi|15967075|ref|NP_387428.1| PROBABLE BIFUNCTIONAL INCLUDES: PHO... 275 3e-72
gi|24115290|ref|NP_709800.1| phosphoribosylaminoimidazolecarboxa... 275 3e-72
gi|26250778|ref|NP_756818.1| Purine biosynthesis protein PurH; P... 274 7e-72
gi|39933108|ref|NP_945384.1| bifunctional purine biosynthesis pr... 270 7e-71
gi|22956468|ref|ZP_00004237.1| COG0138: AICAR transformylase/IMP... 270 1e-70
gi|17936698|ref|NP_533488.1| bifunctional purine biosynthesis pr... 264 5e-69
gi|15890069|ref|NP_355750.1| AGR_C_5117p [Agrobacterium tumefaci... 264 5e-69
gi|48766654|ref|ZP_00271204.1| COG0138: AICAR transformylase/IMP... 264 7e-69
gi|21673159|ref|NP_661224.1| phosphoribosylaminoimidazolecarboxa... 263 2e-68
gi|13473487|ref|NP_105054.1| bifunctional purine biosynthesis pr... 261 6e-68
gi|42527401|ref|NP_972499.1| phosphoribosylaminoimidazolecarboxa... 254 7e-66
gi|49474769|ref|YP_032811.1| Bifunctional purine biosynthesis pr... 253 9e-66
gi|48785095|ref|ZP_00281400.1| COG0138: AICAR transformylase/IMP... 253 1e-65
gi|41720176|ref|ZP_00149015.1| COG0138: AICAR transformylase/IMP... 250 1e-64
gi|19704317|ref|NP_603879.1| Phosphoribosylaminoimidazolecarboxa... 250 1e-64
gi|48767947|ref|ZP_00272299.1| COG0138: AICAR transformylase/IMP... 249 2e-64
gi|28899670|ref|NP_799275.1| phosphoribosylaminoimidazolecarboxa... 248 3e-64
gi|23098204|ref|NP_691670.1| phosphoribosylaminoimidazolecarboxa... 248 4e-64
gi|15600047|ref|NP_253541.1| phosphoribosylaminoimidazolecarboxa... 248 5e-64
gi|30248880|ref|NP_840950.1| probable phosphoribosylaminoimidazo... 248 5e-64
gi|16077720|ref|NP_388534.1| inosine-monophosphate cyclohydrolas... 247 7e-64
gi|32044209|ref|ZP_00141310.1| COG0138: AICAR transformylase/IMP... 247 7e-64
gi|34763390|ref|ZP_00144341.1| PHOSPHORIBOSYLAMINOIMIDAZOLECARBO... 247 7e-64
gi|48850323|ref|ZP_00304565.1| COG0138: AICAR transformylase/IMP... 247 7e-64
gi|49236529|ref|ZP_00330588.1| COG0138: AICAR transformylase/IMP... 247 7e-64
gi|50085531|ref|YP_047041.1| bifunctional protein [Includes: pho... 247 9e-64
gi|23467641|ref|ZP_00123221.1| COG0138: AICAR transformylase/IMP... 247 9e-64
gi|28828110|gb|AAO50793.1| similar to Thermoanaerobacter tengcon... 247 9e-64
gi|48870005|ref|ZP_00322737.1| COG0138: AICAR transformylase/IMP... 246 1e-63
gi|46113247|ref|ZP_00200726.1| COG0138: AICAR transformylase/IMP... 246 1e-63
gi|46132909|ref|ZP_00171691.2| COG0138: AICAR transformylase/IMP... 246 1e-63
gi|16803805|ref|NP_465290.1| Bifunctional phosphoribosylaminoimi... 246 1e-63
gi|17545223|ref|NP_518625.1| PROBABLE BIFUNCTIONAL : PHOSPHORIBO... 246 2e-63
gi|46316085|ref|ZP_00216665.1| COG0138: AICAR transformylase/IMP... 246 2e-63
gi|46321145|ref|ZP_00221525.1| COG0138: AICAR transformylase/IMP... 245 3e-63
gi|16123865|ref|NP_407178.1| bifunctional purine biosynthesis pr... 245 3e-63
gi|22124417|ref|NP_667840.1| phosphoribosylaminoimidazolecarboxa... 245 3e-63
gi|39995716|ref|NP_951667.1| phosphoribosylaminoimidazolecarboxa... 245 3e-63
gi|46143527|ref|ZP_00135055.2| COG0138: AICAR transformylase/IMP... 245 3e-63
gi|16800943|ref|NP_471211.1| Bifunctional phosphoribosylaminoimi... 243 1e-62
gi|48833088|ref|ZP_00290112.1| COG0138: AICAR transformylase/IMP... 243 1e-62
gi|49479086|ref|YP_034620.1| phosphoribosylaminoimidazole carbox... 243 1e-62
gi|30018541|ref|NP_830172.1| IMP cyclohydrolase [Bacillus cereus... 243 1e-62
gi|48860390|ref|ZP_00314315.1| COG0138: AICAR transformylase/IMP... 243 1e-62
gi|21398245|ref|NP_654230.1| AICARFT_IMPCHas, AICARFT/IMPCHase b... 243 2e-62
gi|49476249|ref|YP_034290.1| Bifunctional purine biosynthesis pr... 243 2e-62
gi|47569943|ref|ZP_00240608.1| phosphoribosylaminoimidazolecarbo... 242 3e-62
gi|42779408|ref|NP_976655.1| phosphoribosylaminoimidazolecarboxa... 242 3e-62
gi|46907995|ref|YP_014384.1| phosphoribosylaminoimidazolecarboxa... 241 5e-62
gi|48844690|ref|ZP_00298991.1| COG0138: AICAR transformylase/IMP... 241 5e-62
gi|23113954|ref|ZP_00099286.1| COG0138: AICAR transformylase/IMP... 240 8e-62
gi|16767430|ref|NP_463045.1| phosphoribosylaminoimidazolecarboxa... 240 8e-62
gi|16124341|ref|NP_418905.1| phosphoribosylaminoimidazolecarboxa... 240 1e-61
gi|33239750|ref|NP_874692.1| AICAR transformylase/IMP cyclohydro... 239 2e-61
gi|50119201|ref|YP_048368.1| bifunctional purine biosynthesis pr... 239 2e-61
gi|23104499|ref|ZP_00090963.1| COG0138: AICAR transformylase/IMP... 239 2e-61
gi|29143769|ref|NP_807111.1| phosphoribosylaminoimidazolecarboxa... 238 4e-61
gi|20807087|ref|NP_622258.1| AICAR transformylase/IMP cyclohydro... 237 7e-61
gi|21229973|ref|NP_635890.1| bifunctional purine biosynthesis pr... 237 7e-61
gi|15602087|ref|NP_245159.1| PurH [Pasteurella multocida Pm70] >... 237 9e-61
gi|21241284|ref|NP_640866.1| bifunctional purine biosynthesis pr... 236 2e-60
gi|16762281|ref|NP_457898.1| phosphoribosylaminoimidazolecarboxa... 236 2e-60
gi|34496001|ref|NP_900216.1| phosphoribosylaminoimidazolecarboxa... 236 2e-60
gi|46129145|ref|ZP_00155824.2| COG0138: AICAR transformylase/IMP... 235 3e-60
gi|15606962|ref|NP_214344.1| phosphoribosylaminoimidazolecarboxa... 235 3e-60
gi|26991502|ref|NP_746927.1| phosphoribosylaminoimidazolecarboxa... 234 4e-60
gi|16272827|ref|NP_439048.1| phosphoribosylaminoimidazolecarboxa... 234 8e-60
gi|48865780|ref|ZP_00319638.1| COG0138: AICAR transformylase/IMP... 233 1e-59
gi|15640305|ref|NP_229932.1| phosphoribosylaminoimidazolecarboxa... 233 2e-59
gi|42631211|ref|ZP_00156749.1| COG0138: AICAR transformylase/IMP... 232 2e-59
gi|29376325|ref|NP_815479.1| phosphoribosylaminoimidazolecarboxa... 232 2e-59
gi|24214983|ref|NP_712464.1| IMP cyclohydrolase [Leptospira inte... 232 3e-59
gi|45657525|ref|YP_001611.1| PurH [Leptospira interrogans serova... 232 3e-59
gi|33864124|ref|NP_895684.1| AICARFT/IMPCHase bienzyme:Methylgly... 232 3e-59
gi|27364630|ref|NP_760158.1| AICAR transformylase/IMP cyclohydro... 231 5e-59
gi|22995410|ref|ZP_00039887.1| COG0138: AICAR transformylase/IMP... 231 5e-59
gi|37524504|ref|NP_927848.1| phosphoribosylaminoimidazolecarboxa... 231 5e-59
gi|48825155|ref|ZP_00286439.1| COG0138: AICAR transformylase/IMP... 231 5e-59
gi|15838569|ref|NP_299257.1| bifunctional purine biosynthesis pr... 231 6e-59
gi|32129929|sp|Q9PC10|PUR9_XYLFA Bifunctional purine biosynthesi... 231 6e-59
gi|15794127|ref|NP_283949.1| putative bifunctional purine biosyn... 230 8e-59
gi|28198733|ref|NP_779047.1| bifunctional purine biosynthesis pr... 230 8e-59
gi|17230585|ref|NP_487133.1| bifunctional purine biosynthesis pr... 229 1e-58
gi|37520128|ref|NP_923505.1| phosphoribosyl aminoimidazole carbo... 229 1e-58
gi|17986517|ref|NP_539151.1| PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXA... 229 2e-58
gi|23128034|ref|ZP_00109890.1| COG0138: AICAR transformylase/IMP... 229 2e-58
gi|48890989|ref|ZP_00324573.1| COG0138: AICAR transformylase/IMP... 229 2e-58
gi|48732254|ref|ZP_00265997.1| COG0138: AICAR transformylase/IMP... 229 2e-58
gi|23470747|ref|ZP_00126079.1| COG0138: AICAR transformylase/IMP... 228 4e-58
gi|28379214|ref|NP_786106.1| bifunctional protein: phosphoribosy... 228 5e-58
gi|15673500|ref|NP_267674.1| bifunctional purine biosynthesis pr... 228 5e-58
gi|28871981|ref|NP_794600.1| phosphoribosylaminoimidazolecarboxa... 227 7e-58
gi|15613196|ref|NP_241499.1| phosphoribosylaminoimidazolecarboxa... 227 7e-58
gi|33860824|ref|NP_892385.1| AICARFT/IMPCHase bienzyme:Methylgly... 227 9e-58
gi|22997607|ref|ZP_00041836.1| COG0138: AICAR transformylase/IMP... 227 9e-58
gi|33602975|ref|NP_890535.1| bifunctional purine biosynthesis pr... 227 9e-58
gi|551903|gb|AAB59070.1| purH 226 1e-57
gi|33598082|ref|NP_885725.1| bifunctional purine biosynthesis pr... 226 2e-57
gi|33594299|ref|NP_881943.1| bifunctional purine biosynthesis pr... 225 3e-57
gi|29653686|ref|NP_819378.1| phosphoribosylaminoimidazolecarboxa... 224 5e-57
gi|41690727|ref|ZP_00147259.1| COG0138: AICAR transformylase/IMP... 224 6e-57
gi|47574491|ref|ZP_00244527.1| COG0138: AICAR transformylase/IMP... 224 8e-57
gi|49483237|ref|YP_040461.1| putative bifunctional purine biosyn... 223 1e-56
gi|15924063|ref|NP_371597.1| bifunctional purine biosynthesis pr... 222 2e-56
gi|2072373|emb|CAA70450.1| phosphoribosylaminoimidazolecarboxami... 222 3e-56
gi|279479|pir||DTEBPH purH bifunctional enzyme - Salmonella typh... 221 4e-56
gi|15676875|ref|NP_274020.1| phosphoribosylaminoimidazolecarboxa... 221 4e-56
gi|49485912|ref|YP_043133.1| putative bifunctional purine biosyn... 221 5e-56
gi|21282685|ref|NP_645773.1| bifunctional purine biosynthesis pr... 221 5e-56
gi|45916762|ref|ZP_00195780.2| COG0138: AICAR transformylase/IMP... 221 7e-56
gi|24372037|ref|NP_716079.1| phosphoribosylaminoimidazolecarboxa... 220 9e-56
gi|46914928|emb|CAG21703.1| putative osphoribosylaminoimidazolec... 219 3e-55
gi|15792282|ref|NP_282105.1| phosphoribosylaminoimidazolecarboxa... 218 3e-55
gi|6179961|gb|AAF05727.1| PurH [Mycobacterium avium subsp. parat... 217 7e-55
gi|8927416|gb|AAF82069.1| formyltransferase [Mycobacterium avium... 217 7e-55
gi|46198869|ref|YP_004536.1| phosphoribosylaminoimidazolecarboxa... 217 1e-54
gi|22299090|ref|NP_682337.1| phosphoribosyl aminoimidazole carbo... 217 1e-54
gi|48861221|ref|ZP_00315125.1| COG0138: AICAR transformylase/IMP... 216 1e-54
gi|27467689|ref|NP_764326.1| phosphoribosylaminoimidazolecarboxa... 216 2e-54
gi|11878280|gb|AAG40879.1| phosphoribosylaminoimidazolecarboxami... 216 2e-54
gi|32171642|sp|Q8DWK8|PUR9_STRMU Bifunctional purine biosynthesi... 216 2e-54
gi|32476255|ref|NP_869249.1| bifunctional purine biosynthesis pr... 216 2e-54
gi|24378565|ref|NP_720520.1| putative phosphoribosylaminoimidazo... 216 2e-54
gi|41407001|ref|NP_959837.1| PurH [Mycobacterium avium subsp. pa... 215 3e-54
gi|45645210|sp|Q9RAJ5|PUR9_MYCPA Bifunctional purine biosynthesi... 215 3e-54
gi|21909560|ref|NP_663828.1| putative phosphoribosyl carboxyamid... 215 4e-54
gi|19745224|ref|NP_606360.1| putative phosphoribosyl carboxyamid... 214 6e-54
gi|48852332|ref|ZP_00306520.1| COG0138: AICAR transformylase/IMP... 214 6e-54
gi|38233436|ref|NP_939203.1| bifunctional purine biosynthesis pr... 214 6e-54
gi|42520702|ref|NP_966617.1| phosphoribosylaminoimidazolecarboxa... 213 1e-53
gi|42761313|dbj|BAD11556.1| putative aminoimidazolecarboximide r... 213 1e-53
gi|15608097|ref|NP_215472.1| purH [Mycobacterium tuberculosis H3... 213 1e-53
gi|42761312|dbj|BAD11555.1| putative aminoimidazolecarboximide r... 213 1e-53
gi|15899995|ref|NP_344599.1| phosphoribosylaminoimidazolecarboxa... 213 2e-53
gi|30686280|ref|NP_850240.1| AICARFT/IMPCHase bienzyme family pr... 212 2e-53
gi|32171721|sp|Q9RHX6|PUR9_CORAM Bifunctional purine biosynthesi... 212 2e-53
gi|7433571|pir||T00485 probable phosphoribosylaminoimidazolecarb... 212 2e-53
gi|46106435|ref|ZP_00187243.2| COG0138: AICAR transformylase/IMP... 211 7e-53
gi|22536215|ref|NP_687066.1| phosphoribosylaminoimidazolecarboxa... 210 9e-53
gi|33864785|ref|NP_896344.1| AICARFT/IMPCHase bienzyme:Methylgly... 210 9e-53
gi|48105312|ref|XP_395924.1| similar to 5-aminoimidazole-4-carbo... 210 1e-52
gi|32171638|sp|Q8DRM1|PUR9_STRR6 Bifunctional purine biosynthesi... 209 2e-52
gi|15902095|ref|NP_357645.1| Phosphoribosylaminoimidazolecarboxa... 209 2e-52
gi|34558180|ref|NP_907995.1| PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXA... 208 3e-52
gi|15826983|ref|NP_301246.1| putative phosphoribosylaminoimidazo... 208 4e-52
gi|18309668|ref|NP_561602.1| bifunctional purine biosynthesis pr... 208 4e-52
gi|50591514|ref|ZP_00332823.1| COG0138: AICAR transformylase/IMP... 207 6e-52
gi|28412960|gb|AAO40252.1| aminoimidazolecarboximide ribonucleot... 207 6e-52
gi|16332321|ref|NP_443049.1| phosphoribosyl aminoimidazole carbo... 207 6e-52
gi|32172442|sp|P74741|PUR9_SYNY3 Bifunctional purine biosynthesi... 207 6e-52
gi|46362943|ref|ZP_00225750.1| COG0138: AICAR transformylase/IMP... 207 8e-52
gi|25027493|ref|NP_737547.1| phosphoribosylaminoimidazolecarboxa... 206 1e-51
gi|15616660|ref|NP_239872.1| phosphoribosylaminoimidazolecarboxa... 205 3e-51
gi|45523332|ref|ZP_00174706.1| COG0138: AICAR transformylase/IMP... 204 6e-51
gi|48477817|ref|YP_023523.1| phosphoribosylaminoimidazolecarboxa... 203 1e-50
gi|23465313|ref|NP_695916.1| bifunctional purine biosynthesis pr... 201 4e-50
gi|19552088|ref|NP_600090.1| phosphoribosylaminoimidazolecarboxa... 201 7e-50
gi|50843207|ref|YP_056434.1| Phosphoribosylaminoimidazolecarboxa... 199 2e-49
gi|48836815|ref|ZP_00293810.1| COG0138: AICAR transformylase/IMP... 198 4e-49
gi|29829987|ref|NP_824621.1| putative bifunctional purine biosyn... 198 4e-49
gi|23120370|ref|ZP_00103060.1| COG0138: AICAR transformylase/IMP... 197 6e-49
gi|21672325|ref|NP_660392.1| bifunctional purine biosynthesis pr... 197 8e-49
gi|46308297|ref|ZP_00210491.1| COG0138: AICAR transformylase/IMP... 196 2e-48
gi|21223192|ref|NP_628971.1| bifunctional purine biosynthesis pr... 196 2e-48
gi|32171722|sp|Q9RW01|PUR9_DEIRA Bifunctional purine biosynthesi... 194 5e-48
gi|15805894|ref|NP_294592.1| phosphoribosylaminoimidazolecarboxa... 194 5e-48
gi|7497695|pir||T34176 hypothetical protein C49H3.7 - Caenorhabd... 194 7e-48
gi|15894674|ref|NP_348023.1| AICAR transformylase/IMP cyclohydro... 193 1e-47
gi|46191230|ref|ZP_00206721.1| COG0138: AICAR transformylase/IMP... 191 7e-47
gi|28211588|ref|NP_782532.1| phosphoribosylaminoimidazolecarboxa... 190 1e-46
gi|28493051|ref|NP_787212.1| phosphoribosylaminoimidazolecarboxa... 189 3e-46
gi|50876503|emb|CAG36343.1| probable bifunctional purine biosynt... 188 5e-46
gi|29349220|ref|NP_812723.1| phosphoribosylaminoimidazole carbox... 184 7e-45
gi|16081235|ref|NP_393539.1| purH bifunctional enzyme related pr... 183 2e-44
gi|32171613|sp|Q89B23|PUR9_BUCBP Bifunctional purine biosynthesi... 181 6e-44
gi|27904544|ref|NP_777670.1| phosphoribosylaminoimidazolecarboxa... 181 6e-44
gi|48867093|ref|ZP_00320711.1| COG0138: AICAR transformylase/IMP... 179 2e-43
gi|34541079|ref|NP_905558.1| phosphoribosylaminoimidazolecarboxa... 178 4e-43
gi|32265982|ref|NP_860014.1| AICAR transformylase PurH [Helicoba... 174 9e-42
gi|33519998|ref|NP_878830.1| phosphoribosylaminoimidazolecarboxa... 173 1e-41
gi|33152721|ref|NP_874074.1| bifunctional purine biosynthesis pr... 172 3e-41
gi|42524398|ref|NP_969778.1| IMP cyclohydrolase [Bdellovibrio ba... 172 3e-41
gi|48856971|ref|ZP_00311128.1| COG0138: AICAR transformylase/IMP... 169 2e-40
gi|13540847|ref|NP_110535.1| AICAR transformylase/IMP cyclohydro... 166 3e-39
gi|32491260|ref|NP_871514.1| purH [Wigglesworthia glossinidia en... 160 8e-38
gi|2145614|pir||S54424 phosphoribosylaminoimidazolecarboxamide f... 159 3e-37
gi|22973685|ref|ZP_00020227.1| hypothetical protein [Chloroflexu... 152 2e-35
gi|46202491|ref|ZP_00208542.1| COG0138: AICAR transformylase/IMP... 150 1e-34
gi|3248935|gb|AAD09926.1| phosphoribosylaminoimidazolecarboxamid... 144 1e-32
gi|34860201|ref|XP_227632.2| similar to 5-aminoimidazole-4-carbo... 143 1e-32
gi|23474350|ref|ZP_00129644.1| COG0138: AICAR transformylase/IMP... 136 2e-30
gi|15644005|ref|NP_229054.1| phosphoribosylaminoimidazolecarboxa... 134 8e-30
gi|46581637|ref|YP_012445.1| IMP cyclohydrolase, putative [Desul... 131 5e-29
gi|46202492|ref|ZP_00208543.1| COG0138: AICAR transformylase/IMP... 123 2e-26
gi|13277324|emb|CAC34383.1| bifunctional protein [Platichthys fl... 108 5e-22
gi|23475684|ref|ZP_00130966.1| COG0138: AICAR transformylase/IMP... 105 4e-21
gi|7415859|dbj|BAA93563.1| phosphoribosyl aminoimiddazol carboxa... 104 7e-21
gi|50876630|emb|CAG36470.1| related to bifunctional purine biosy... 101 8e-20
gi|46581608|ref|YP_012416.1| phosphoribosylaminoimidazolecarboxa... 101 8e-20
gi|46254458|gb|AAS86202.1| 5-aminoimidazole-4-carboxamide ribonu... 85 7e-15
gi|48867242|ref|ZP_00320814.1| COG0138: AICAR transformylase/IMP... 75 4e-12
gi|46520130|gb|AAT00453.1| PurH [Xanthomonas oryzae pv. oryzae] 74 1e-11
gi|15789661|ref|NP_279485.1| phosphoribosylaminoimidazole-succin... 74 1e-11
gi|32028651|ref|ZP_00131807.1| COG0138: AICAR transformylase/IMP... 70 2e-10
gi|41724792|ref|ZP_00151602.1| COG0138: AICAR transformylase/IMP... 69 4e-10
gi|2500021|sp|Q46480|PUR9_CHRVI Bifunctional purine biosynthesis... 69 5e-10
gi|48290845|dbj|BAB63412.2| phosphoribosyl carboxyamide aminoimi... 64 2e-08
gi|48290857|dbj|BAB63433.2| phosphoribosyl carboxyamide aminoimi... 63 2e-08
gi|48290842|dbj|BAB20850.2| phosphoribosyl carboxyamide aminoimi... 63 2e-08
gi|48290854|dbj|BAB63427.2| phosphoribosyl carboxyamide aminoimi... 63 2e-08
gi|31195923|ref|XP_306909.1| ENSANGP00000000436 [Anopheles gambi... 61 1e-07
gi|11499399|ref|NP_070638.1| inosine monophosphate cyclohydrolas... 61 1e-07
gi|2465560|gb|AAB72185.1| phosphoribosylaminoimidazole-carboxami... 60 2e-07
gi|45508763|ref|ZP_00161100.1| COG0138: AICAR transformylase/IMP... 58 7e-07
gi|23115455|ref|ZP_00100516.1| COG0138: AICAR transformylase/IMP... 57 2e-06
gi|45511952|ref|ZP_00163519.1| COG0138: AICAR transformylase/IMP... 55 6e-06
gi|50260348|gb|EAL23007.1| hypothetical protein CNBA7740 [Crypto... 49 6e-04
gi|33322574|gb|AAQ07018.1| phosphoribosylaminoimidazolecarboxami... 44 0.019
gi|46206019|ref|ZP_00047798.2| COG0138: AICAR transformylase/IMP... 43 0.025
gi|20095102|ref|NP_614949.1| Carbamoylphosphate synthase large s... 42 0.042
gi|12082235|dbj|BAB20852.1| phosphoribosyl carboxyamide aminoimi... 42 0.042
gi|33240347|ref|NP_875289.1| Carbamoylphosphate synthase large s... 42 0.055
gi|6552726|gb|AAF16526.1| ADP-forming, carbamate-phosphorylating... 41 0.094
gi|48833419|ref|ZP_00290438.1| COG0138: AICAR transformylase/IMP... 41 0.12
gi|48846164|ref|ZP_00300430.1| COG0458: Carbamoylphosphate synth... 40 0.27
gi|21231291|ref|NP_637208.1| carbamoyl-phosphate synthase large ... 40 0.27
gi|22095491|sp|P58942|CARB_XANAC Carbamoyl-phosphate synthase la... 40 0.27
gi|23013681|ref|ZP_00053549.1| COG0458: Carbamoylphosphate synth... 40 0.27
gi|33322587|gb|AAQ07025.1| phosphoribosylaminoimidazolecarboxami... 40 0.27
gi|21242606|ref|NP_642188.1| carbamoyl-phosphate synthase large ... 40 0.27
gi|41689213|ref|ZP_00145747.1| COG0458: Carbamoylphosphate synth... 39 0.36
gi|39996378|ref|NP_952329.1| carbamoyl-phosphate synthase, large... 39 0.36
gi|48848181|ref|ZP_00302427.1| COG0458: Carbamoylphosphate synth... 39 0.46
gi|15643323|ref|NP_228367.1| carbamoyl-phosphate synthase, large... 38 0.79
gi|49069864|ref|XP_399221.1| hypothetical protein UM01606.1 [Ust... 38 1.0
gi|23113682|ref|ZP_00099038.1| COG0458: Carbamoylphosphate synth... 37 1.8
gi|22971060|ref|ZP_00018058.1| hypothetical protein [Chloroflexu... 37 1.8
gi|15603370|ref|NP_246444.1| CarB [Pasteurella multocida Pm70] >... 36 3.0
gi|48477971|ref|YP_023677.1| carbamoyl-phosphate synthase [Picro... 36 3.0
gi|29374808|ref|NP_813960.1| conjugal transfer protein, putative... 36 3.0
gi|18311554|ref|NP_563488.1| carbamoyl-phosphate synthetase cata... 36 3.0
gi|31231655|ref|XP_318561.1| ENSANGP00000019607 [Anopheles gambi... 36 3.9
gi|42526737|ref|NP_971835.1| pentapeptide repeat family protein ... 36 3.9
gi|27467797|ref|NP_764434.1| carbamoyl-phosphate synthase large ... 36 3.9
gi|41723686|ref|ZP_00150596.1| COG0458: Carbamoylphosphate synth... 36 3.9
gi|31231666|ref|XP_318563.1| ENSANGP00000023306 [Anopheles gambi... 36 3.9
gi|31231660|ref|XP_318562.1| ENSANGP00000022873 [Anopheles gambi... 36 3.9
gi|15679751|ref|NP_276869.1| collagenase [Methanothermobacter th... 35 5.1
gi|456984|gb|AAB29457.1| ryanodine receptor, calcium release cha... 35 6.7
gi|630870|pir||S40450 ryanodine receptor/calcium release channel... 35 6.7
gi|2160476|dbj|BAA41470.1| ryanodine receptor homologue [Drosoph... 35 6.7
gi|17352469|ref|NP_476993.1| CG10844-PC [Drosophila melanogaster... 35 6.7
gi|17352465|ref|NP_476991.1| CG10844-PA [Drosophila melanogaster... 35 6.7
gi|2160478|dbj|BAA04212.1| ryanodine receptor homologue [Drosoph... 35 6.7
gi|2160477|dbj|BAA41471.1| ryanodine receptor homologue [Drosoph... 35 6.7
gi|15791854|ref|NP_281677.1| aldehyde dehydrogenase C-terminus [... 35 6.7
gi|17352471|ref|NP_476994.1| CG10844-PD [Drosophila melanogaster... 35 6.7
gi|17352467|ref|NP_476992.1| CG10844-PB [Drosophila melanogaster... 35 6.7
gi|27467798|ref|NP_764435.1| orotidine-5-phosphate decarboxylase... 35 8.8
gi|50420269|ref|XP_458667.1| unnamed protein product [Debaryomyc... 35 8.8
gi|23489953|gb|EAA21840.1| hypothetical protein [Plasmodium yoel... 35 8.8
>gi|25145656|ref|NP_741451.1| IMP cyclohydrolase (4I663)
[Caenorhabditis elegans]
Length = 666
Score = 1334 bits (3453), Expect = 0.0
Identities = 666/666 (100%), Positives = 666/666 (100%)
Frame = +1
Query: 1 MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA 180
MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA
Sbjct: 1 MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA 60
Query: 181 KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV 360
KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV
Sbjct: 61 KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV 120
Query: 361 VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL 540
VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL
Sbjct: 121 VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL 180
Query: 541 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 720
KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL
Sbjct: 181 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 240
Query: 721 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL 900
YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL
Sbjct: 241 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL 300
Query: 901 NETEAACCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIA 1080
NETEAACCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIA
Sbjct: 301 NETEAACCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIA 360
Query: 1081 LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 1260
LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT
Sbjct: 361 LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 420
Query: 1261 VFGLRLRQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKS 1440
VFGLRLRQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKS
Sbjct: 421 VFGLRLRQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKS 480
Query: 1441 LFQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW 1620
LFQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW
Sbjct: 481 LFQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW 540
Query: 1621 LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ 1800
LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ
Sbjct: 541 LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ 600
Query: 1801 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG 1980
WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG
Sbjct: 601 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG 660
Query: 1981 LRLFHH 1998
LRLFHH
Sbjct: 661 LRLFHH 666
>gi|25145659|ref|NP_741452.1| IMP cyclohydrolase (67.4 kD) (4I663)
[Caenorhabditis elegans]
gi|22532967|gb|AAL27234.2| Hypothetical protein C55F2.1b
[Caenorhabditis elegans]
Length = 615
Score = 1204 bits (3114), Expect = 0.0
Identities = 615/666 (92%), Positives = 615/666 (92%)
Frame = +1
Query: 1 MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA 180
MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA
Sbjct: 1 MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA 60
Query: 181 KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV 360
KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV
Sbjct: 61 KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV 120
Query: 361 VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL 540
VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL
Sbjct: 121 VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL 180
Query: 541 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 720
KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL
Sbjct: 181 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 240
Query: 721 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL 900
YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL
Sbjct: 241 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL 300
Query: 901 NETEAACCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIA 1080
NETEAACCMVSDLPIDTKKPSLAAAYARAR GADRMSSFGDFIA
Sbjct: 301 NETEAACCMVSDLPIDTKKPSLAAAYARAR-----------------GADRMSSFGDFIA 343
Query: 1081 LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 1260
LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT
Sbjct: 344 LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 403
Query: 1261 VFGLRLRQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKS 1440
VFGLRLRQKRNNAVINAETFNNVVGSANE
Sbjct: 404 VFGLRLRQKRNNAVINAETFNNVVGSANE------------------------------- 432
Query: 1441 LFQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW 1620
LNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW
Sbjct: 433 ---LNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW 489
Query: 1621 LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ 1800
LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ
Sbjct: 490 LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ 549
Query: 1801 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG 1980
WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG
Sbjct: 550 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG 609
Query: 1981 LRLFHH 1998
LRLFHH
Sbjct: 610 LRLFHH 615
>gi|39595034|emb|CAE70902.1| Hypothetical protein CBG17698
[Caenorhabditis briggsae]
Length = 648
Score = 1199 bits (3101), Expect = 0.0
Identities = 599/666 (89%), Positives = 625/666 (92%)
Frame = +1
Query: 1 MLEIEFYKTIDLIQYIDELCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTA 180
M IEFYKTI LIQYIDELCEMTDGK+LAIISVSDKTGL+PLA GLVSAGL L+ASGGTA
Sbjct: 1 MWHIEFYKTIHLIQYIDELCEMTDGKTLAIISVSDKTGLLPLAEGLVSAGLVLVASGGTA 60
Query: 181 KAIRDQGIDVHDVADVTKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSV 360
KAIRD GI+VHDVAD+TKFPEMLGGRVKTLHPAVHGGILARD+ESDRKDLE HNISFVS+
Sbjct: 61 KAIRDHGINVHDVADITKFPEMLGGRVKTLHPAVHGGILARDSESDRKDLETHNISFVSI 120
Query: 361 VVCNLYPFKKTVQSKDCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL 540
VVCNLYPFKKTVQ +CSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYD+I+SEL
Sbjct: 121 VVCNLYPFKKTVQQSNCSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDNILSEL 180
Query: 541 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 720
KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL
Sbjct: 181 KSGGTTRERRQLLALKAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAEL 240
Query: 721 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPL 900
YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAA+GLPL
Sbjct: 241 YIVEDEMPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAIGLPL 300
Query: 901 NETEAACCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIA 1080
NETE+ACCMVSDLPID KK SLAAAYARAREQDW+I DRLQR APS+GADRMSSFGDFIA
Sbjct: 301 NETESACCMVSDLPIDPKKASLAAAYARAREQDWIINDRLQRFAPSVGADRMSSFGDFIA 360
Query: 1081 LSEKCDELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 1260
LSEKCDELTAKIINREVSDGVVAPD+DPAALSLLAKKKNGNYCVLKINPNYLPSETEERT
Sbjct: 361 LSEKCDELTAKIINREVSDGVVAPDYDPAALSLLAKKKNGNYCVLKINPNYLPSETEERT 420
Query: 1261 VFGLRLRQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKS 1440
VFGLRLRQKRNNAVINAETF NVVG N S+IR ++ + C
Sbjct: 421 VFGLRLRQKRNNAVINAETFTNVVGKEN--SEIREIE-----------TQISRIKC---- 463
Query: 1441 LFQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWW 1620
FQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKA+NWW
Sbjct: 464 -FQLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAVNWW 522
Query: 1621 LRQHPTVLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQ 1800
LRQHPTVLSLPWKNAIKRSEKSNAIDV+CSGVLGSEIA+DQWQQYFNEPVEPLAE++RKQ
Sbjct: 523 LRQHPTVLSLPWKNAIKRSEKSNAIDVMCSGVLGSEIAVDQWQQYFNEPVEPLAEEERKQ 582
Query: 1801 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTG 1980
WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRD++IKEACDEHGITLIHTG
Sbjct: 583 WLSQQTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDEEIKEACDEHGITLIHTG 642
Query: 1981 LRLFHH 1998
LRLFHH
Sbjct: 643 LRLFHH 648
>gi|29570507|gb|AAL27233.2| Hypothetical protein C55F2.1a
[Caenorhabditis elegans]
Length = 420
Score = 850 bits (2195), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Frame = +1
Query: 739 MPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAA 918
MPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAA
Sbjct: 1 MPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAA 60
Query: 919 CCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCD 1098
CCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCD
Sbjct: 61 CCMVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCD 120
Query: 1099 ELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRL 1278
ELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRL
Sbjct: 121 ELTAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRL 180
Query: 1279 RQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNK 1458
RQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNK
Sbjct: 181 RQKRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNK 240
Query: 1459 QAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPT 1638
QAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPT
Sbjct: 241 QAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPT 300
Query: 1639 VLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQT 1818
VLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQT
Sbjct: 301 VLSLPWKNAIKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQT 360
Query: 1819 GVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
GVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH
Sbjct: 361 GVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 420
>gi|24649832|ref|NP_651305.1| CG11089-PA [Drosophila melanogaster]
gi|7301227|gb|AAF56358.1| CG11089-PA [Drosophila melanogaster]
gi|41058144|gb|AAR99120.1| RE29555p [Drosophila melanogaster]
Length = 590
Score = 679 bits (1753), Expect = 0.0
Identities = 347/640 (54%), Positives = 443/640 (69%), Gaps = 1/640 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
+A++SVSDKTGL+ L LV+ G L+ASGGTA ++R G+ V DV+++T PEMLGGRV
Sbjct: 6 IALLSVSDKTGLLDLGKSLVALGFDLVASGGTATSLRGAGLKVRDVSEITGAPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GIL+R T+SD D+ K + +VVCNLYPF TV D ++ +AVENID
Sbjct: 66 KTLHPAVHAGILSRTTDSDLADMRKQGFDLIQLVVCNLYPFASTVAKPDVTLADAVENID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISELK-SGGTTRERRQLLALKAFEHTTSYDE 618
IGGVTLLRAAAKNH+RV+V+C+ DYD ++SELK SG TT E RQ LALKAF HT +YD+
Sbjct: 126 IGGVTLLRAAAKNHQRVTVVCEAVDYDRVLSELKASGNTTVETRQALALKAFTHTATYDD 185
Query: 619 SISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDGLN 798
+IS + R+++ G+G LPLRYG NPHQK A+LY ++P+ VLN SPG+IN+ D LN
Sbjct: 186 AISDYFRKQY-GSGVSQLPLRYGMNPHQK-PAQLYTQLAKLPLTVLNASPGFINLCDALN 243
Query: 799 GWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAAAY 978
GWQLV+EL A ++PAA SFKHVSPAGAAVG+PLN +A CMV DL + LA AY
Sbjct: 244 GWQLVRELKKALQLPAATSFKHVSPAGAAVGVPLNPAQAKLCMVDDL--YEQLTPLATAY 301
Query: 979 ARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAPDF 1158
ARAR GADRMSSFGDF+ALS+ CD +TA+II+REVSDG++A +
Sbjct: 302 ARAR-----------------GADRMSSFGDFVALSDVCDVVTARIISREVSDGIIAAGY 344
Query: 1159 DPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVVGS 1338
+P AL +L KKKNG YC+L+++PNY PS E +T+FGL L QKRN+AVI+A F+NVV
Sbjct: 345 EPEALEILKKKKNGGYCILQMDPNYEPSAVERKTIFGLTLEQKRNDAVIDASLFSNVVSK 404
Query: 1339 ANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQSNS 1518
+ ++ A+ DLIVATIALKY QSNS
Sbjct: 405 RGPLPEV----------------------------------AVRDLIVATIALKYTQSNS 430
Query: 1519 VCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNAID 1698
VC+A GQV+G+GAGQQSRIHCTRLAG+KA NWWLRQHP+V + +K +KR+E SNAID
Sbjct: 431 VCYARDGQVVGIGAGQQSRIHCTRLAGEKADNWWLRQHPSVAGMKFKAGVKRAEISNAID 490
Query: 1699 VLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDCAK 1878
+G +G ++ + Q++ F++ L + + +WL Q +GV + SDAF PFRDN+D A
Sbjct: 491 NYVNGTVGKDMPLSQFEGMFDKAPAQLTSEQKVEWLKQLSGVALGSDAFFPFRDNIDRAS 550
Query: 1879 QFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
GVSY+A P GS D + ACDEHGI + HT LRLFHH
Sbjct: 551 LSGVSYIASPAGSTNDAGVIAACDEHGIIMAHTNLRLFHH 590
>gi|49250888|gb|AAH74584.1| Unknown (protein for MGC:69458) [Xenopus
tropicalis]
Length = 589
Score = 676 bits (1744), Expect = 0.0
Identities = 359/642 (55%), Positives = 446/642 (68%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
+A+ SVSDKTGL+ A L + GL+L+ASGGTAK +RD G+ V DV+++T FPEMLGGRV
Sbjct: 4 IALFSVSDKTGLVEFAQQLSTLGLSLVASGGTAKCLRDAGLSVRDVSEITGFPEMLGGRV 63
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR + D+ DL K S+V VVVCNLYPF KTV + +VEEAVE ID
Sbjct: 64 KTLHPAVHAGILARSSPEDQADLNKLGFSYVRVVVCNLYPFVKTVSAAGVTVEEAVEQID 123
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISELKSG---GTTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+CDP+DY I E+ TT ERR LALKAF HT Y
Sbjct: 124 IGGVTLLRAAAKNHARVTVLCDPSDYKSIAEEMGKSDKKDTTPERRCQLALKAFTHTAQY 183
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
D++IS + R++++ G LPLRYG NPHQ A++Y ++P+ VLNGSPG+IN+ D
Sbjct: 184 DDAISDYFRKQYS-KGTSQLPLRYGINPHQV-PAQIYTRGPQLPLTVLNGSPGFINLCDA 241
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLV+EL +A +PAA SFKHVSPAGAAVG+PL E EA CMV DL T P LA
Sbjct: 242 LNAWQLVRELKNALGLPAATSFKHVSPAGAAVGVPLMEEEAQVCMVQDL-FPTLTP-LAT 299
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDFIA+S+ CD TAKII+REVSDG+VAP
Sbjct: 300 AYARAR-----------------GADRMSSFGDFIAVSDVCDVATAKIISREVSDGIVAP 342
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL +L+KKKNG+YCVL+++P+Y PS+ E R++FGL+L QKRN+AVI+ +NNVV
Sbjct: 343 GYEDEALKILSKKKNGSYCVLQMDPSYEPSDIEIRSIFGLQLEQKRNDAVIDRNLYNNVV 402
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ E+ + A+ DLIVATIALKY QS
Sbjct: 403 TNNKEIPE----------------------------------SAVRDLIVATIALKYTQS 428
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIGMGAGQQSRIHCTRLAGDKA NWWLR HP VL + +K +KR++ SNA
Sbjct: 429 NSVCYAKDGQVIGMGAGQQSRIHCTRLAGDKADNWWLRHHPRVLGMKFKAGVKRADISNA 488
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID SG LG E + QWQ +++P E L ++K W+S+ +GV +SSDAF PF+DN++
Sbjct: 489 IDQYVSGTLGEE-DLPQWQALYDQPPEQLTLAEKKDWISKLSGVALSSDAFFPFKDNLER 547
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV ++A P GS D + +AC+E GI L HT LRLFHH
Sbjct: 548 AKKSGVQFIAAPSGSSADKIVIDACNELGIVLAHTNLRLFHH 589
>gi|48675845|ref|NP_112276.2| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase
[Rattus norvegicus]
gi|47939008|gb|AAH72496.1| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/ [Rattus norvegicus]
Length = 592
Score = 674 bits (1738), Expect = 0.0
Identities = 359/642 (55%), Positives = 445/642 (68%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
LA+ SVSDKTGL+ A L S GL+L+ASGGTAKAIRD G+ V DV+++T FPEMLGGRV
Sbjct: 6 LALFSVSDKTGLVEFARNLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR+ D D+ + + + + VVVCNLYPF KTV S D +VE AVE ID
Sbjct: 66 KTLHPAVHAGILARNIPEDAADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEAAVEQID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISELKSGG---TTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+C+P DY + +E++ G T+ E R+ LALKAF HT Y
Sbjct: 126 IGGVTLLRAAAKNHARVTVVCEPEDYGAVAAEMQGSGNKDTSLETRRHLALKAFTHTAQY 185
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
DE+IS + RR+++ G +PLRYG NPHQ A+LY ++ ++PI VLNG+PG+IN+ D
Sbjct: 186 DEAISDYFRRQYS-KGISQMPLRYGMNPHQ-TPAQLYTLKPKLPITVLNGAPGFINLCDA 243
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLV EL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P LA
Sbjct: 244 LNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDL-YPTLTP-LAI 301
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG+VAP
Sbjct: 302 AYARAR-----------------GADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAP 344
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL +L+KKKNG+YCVL+++ +Y P E E RT+FGLRL QKRNN V++ F+N+V
Sbjct: 345 GYEEEALKILSKKKNGSYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIV 404
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ L + A+ DLIVATIA+KY QS
Sbjct: 405 TKNKD----------------------------------LPESALRDLIVATIAVKYTQS 430
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR+E SNA
Sbjct: 431 NSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEVSNA 490
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID +G +G + +W+ F E E L E ++K+W+ + +GV +SSDAF PFRDNVD
Sbjct: 491 IDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDR 550
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV+Y+ P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 AKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH 592
>gi|1263196|gb|AAA97405.1| AICAR formyltransferase/IMP cyclohydrolase
bifunctional enzyme
Length = 591
Score = 674 bits (1738), Expect = 0.0
Identities = 356/641 (55%), Positives = 446/641 (69%), Gaps = 3/641 (0%)
Frame = +1
Query: 85 AIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRVK 264
A+ SVSDKTGL+ A L + GL L+ASGGTAKA+RD G+ V DV+++T FPEMLGGRVK
Sbjct: 6 ALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVK 65
Query: 265 TLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENIDI 444
TLHPAVH GILAR+ D D+ + + + + VV CNLYPF KTV S +VEEAVE IDI
Sbjct: 66 TLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDI 125
Query: 445 GGVTLLRAAAKNHERVSVICDPADYDHIISELKSG---GTTRERRQLLALKAFEHTTSYD 615
GGVTLLRAAAKNH RV+V+C+P DY + +E++S GT+ E R+ LALKAF HT YD
Sbjct: 126 GGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKGTSLETRRQLALKAFTHTAQYD 185
Query: 616 ESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDGL 795
E+IS + R++++ G +PLRYG NPHQ A+LY ++ ++PI VLNG+PG+IN+ D L
Sbjct: 186 EAISDYFRKQYS-KGVSQMPLRYGMNPHQTP-AQLYTLQPKLPITVLNGAPGFINLCDAL 243
Query: 796 NGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAAA 975
N WQLVKEL +A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P ++AA
Sbjct: 244 NAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDL-YKTLTP-ISAA 301
Query: 976 YARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAPD 1155
YARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG++AP
Sbjct: 302 YARAR-----------------GADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPG 344
Query: 1156 FDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVVG 1335
++ AL++L+KKKNGNYCVL+++ +Y P E E RT+FGL L QKRNN V++ F+NVV
Sbjct: 345 YEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVT 404
Query: 1336 SANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQSN 1515
+ L + A+ DLIVATIA+KY QSN
Sbjct: 405 KNKD----------------------------------LPESALRDLIVATIAVKYTQSN 430
Query: 1516 SVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNAI 1695
SVC+A GQVIG+GAGQQSRIHCTRLAGDKA WWLR HP VLS+ +K +KR+E SNAI
Sbjct: 431 SVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAI 490
Query: 1696 DVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDCA 1875
D +G +G + + +W+ F E E L E ++K+W+ + T V +SSDAF PFRDNVD A
Sbjct: 491 DQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRA 550
Query: 1876 KQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
K+ GV+Y+A P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 KRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 591
>gi|28373618|pdb|1M9N|A Chain A, Crystal Structure Of The Homodimeric
Bifunctional Transformylase And Cyclohydrolase Enzyme
Avian Atic In Complex With Aicar And Xmp At 1.93
Angstroms.
gi|28373619|pdb|1M9N|B Chain B, Crystal Structure Of The Homodimeric
Bifunctional Transformylase And Cyclohydrolase Enzyme
Avian Atic In Complex With Aicar And Xmp At 1.93
Angstroms.
gi|37927353|pdb|1OZ0|A Chain A, Crystal Structure Of The Homodimeric
Bifunctional Transformylase And Cyclohydrolase Enzyme
Avian Atic In Complex With A Multisubstrate Adduct
Inhibitor Beta-Dadf.
gi|37927354|pdb|1OZ0|B Chain B, Crystal Structure Of The Homodimeric
Bifunctional Transformylase And Cyclohydrolase Enzyme
Avian Atic In Complex With A Multisubstrate Adduct
Inhibitor Beta-Dadf
Length = 613
Score = 673 bits (1737), Expect = 0.0
Identities = 362/648 (55%), Positives = 444/648 (67%), Gaps = 3/648 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M + LA++SVS+K GL+ A L + GL LIASGGTA A+RD G+ V DV+D+T FPE
Sbjct: 21 MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPE 80
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
MLGGRVKTLHPAVH GILAR+ D D+ K + S V VVVCNLYPF KTV S +V E
Sbjct: 81 MLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPE 140
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL---KSGGTTRERRQLLALKAF 594
AVE IDIGGV LLRAAAKNH RV+V+CDPADY + E+ K T+ E R+ LALKAF
Sbjct: 141 AVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASKDKDTSVETRRHLALKAF 200
Query: 595 EHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGY 774
HT YD +IS + R+ ++ G LPLRYG NPHQ A+LY ++P+ V+NGSPG+
Sbjct: 201 THTAQYDAAISDYFRKEYS-KGVSQLPLRYGMNPHQ-SPAQLYTTRPKLPLTVVNGSPGF 258
Query: 775 INILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTK 954
IN+ D LN WQLVKEL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T
Sbjct: 259 INLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCMVHDLH-KTL 317
Query: 955 KPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVS 1134
P LA+AYAR+R GADRMSSFGDFIALS+ CD TAKII+REVS
Sbjct: 318 TP-LASAYARSR-----------------GADRMSSFGDFIALSDICDVPTAKIISREVS 359
Query: 1135 DGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAE 1314
DGVVAP ++ AL +L+KKKNG YCVL+++PNY P + E RT++GL+L QKRNNAVI+
Sbjct: 360 DGVVAPGYEEEALKILSKKKNGGYCVLQMDPNYEPDDNEIRTLYGLQLMQKRNNAVIDRS 419
Query: 1315 TFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIA 1494
F N+V + N+ L + A+ DLIVA+IA
Sbjct: 420 LFKNIV-TKNKT---------------------------------LPESAVRDLIVASIA 445
Query: 1495 LKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKR 1674
+KY QSNSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR
Sbjct: 446 VKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKR 505
Query: 1675 SEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPF 1854
+E SNAID +G +G + + +WQ F E L E ++KQW+++ T V +SSDAF PF
Sbjct: 506 AEVSNAIDQYVTGTIGEDEDLVKWQAMFEEVPAQLTEAEKKQWIAKLTAVSLSSDAFFPF 565
Query: 1855 RDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
RDNVD AK+ GV ++ P GS D+ + EAC+E GITLIHT LRLFHH
Sbjct: 566 RDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH 613
>gi|45384004|ref|NP_990509.1|
5-aminoimidazole-4-carboxamide-ribonucleotide
transformylase-IMP cyclohydrolase;
5-aminoimidazole-4-carboxamide-ribonucleotide
transformylase-IMP cyclohydrolase, ATIC [Gallus gallus]
gi|400901|sp|P31335|PUR9_CHICK Bifunctional purine biosynthesis
protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide formyltransferase
(AICAR transformylase); IMP cyclohydrolase (Inosinicase)
(IMP synthetase) (ATIC)]
gi|279480|pir||DTCHPH purH bifunctional enzyme - chicken
gi|238786|gb|AAB20309.1|
5-aminoimidazole-4-carboxamide-ribonucleotide
transformylase-IMP cyclohydrolase; ATIC [Gallus gallus]
Length = 593
Score = 673 bits (1737), Expect = 0.0
Identities = 362/648 (55%), Positives = 444/648 (67%), Gaps = 3/648 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M + LA++SVS+K GL+ A L + GL LIASGGTA A+RD G+ V DV+D+T FPE
Sbjct: 1 MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPE 60
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
MLGGRVKTLHPAVH GILAR+ D D+ K + S V VVVCNLYPF KTV S +V E
Sbjct: 61 MLGGRVKTLHPAVHAGILARNIPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPE 120
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL---KSGGTTRERRQLLALKAF 594
AVE IDIGGV LLRAAAKNH RV+V+CDPADY + E+ K T+ E R+ LALKAF
Sbjct: 121 AVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASKDKDTSVETRRHLALKAF 180
Query: 595 EHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGY 774
HT YD +IS + R+ ++ G LPLRYG NPHQ A+LY ++P+ V+NGSPG+
Sbjct: 181 THTAQYDAAISDYFRKEYS-KGVSQLPLRYGMNPHQ-SPAQLYTTRPKLPLTVVNGSPGF 238
Query: 775 INILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTK 954
IN+ D LN WQLVKEL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T
Sbjct: 239 INLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCMVHDLH-KTL 297
Query: 955 KPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVS 1134
P LA+AYAR+R GADRMSSFGDFIALS+ CD TAKII+REVS
Sbjct: 298 TP-LASAYARSR-----------------GADRMSSFGDFIALSDICDVPTAKIISREVS 339
Query: 1135 DGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAE 1314
DGVVAP ++ AL +L+KKKNG YCVL+++PNY P + E RT++GL+L QKRNNAVI+
Sbjct: 340 DGVVAPGYEEEALKILSKKKNGGYCVLQMDPNYEPDDNEIRTLYGLQLMQKRNNAVIDRS 399
Query: 1315 TFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIA 1494
F N+V + N+ L + A+ DLIVA+IA
Sbjct: 400 LFKNIV-TKNKT---------------------------------LPESAVRDLIVASIA 425
Query: 1495 LKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKR 1674
+KY QSNSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR
Sbjct: 426 VKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKR 485
Query: 1675 SEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPF 1854
+E SNAID +G +G + + +WQ F E L E ++KQW+++ T V +SSDAF PF
Sbjct: 486 AEVSNAIDQYVTGTIGEDEDLVKWQAMFEEVPAQLTEAEKKQWIAKLTAVSLSSDAFFPF 545
Query: 1855 RDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
RDNVD AK+ GV ++ P GS D+ + EAC+E GITLIHT LRLFHH
Sbjct: 546 RDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH 593
>gi|20127454|ref|NP_004035.2| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase;
AICARFT/IMPCHASE [Homo sapiens]
gi|23831360|sp|P31939|PUR9_HUMAN Bifunctional purine biosynthesis
protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide formyltransferase
(AICAR transformylase); IMP cyclohydrolase (Inosinicase)
(IMP synthetase) (ATIC)]
gi|2117697|pir||JC4642 purH bifunctional enzyme - human
gi|46015217|pdb|1PKX|A Chain A, Crystal Structure Of Human Atic In
Complex With Xmp
gi|46015218|pdb|1PKX|B Chain B, Crystal Structure Of Human Atic In
Complex With Xmp
gi|46015219|pdb|1PKX|C Chain C, Crystal Structure Of Human Atic In
Complex With Xmp
gi|46015220|pdb|1PKX|D Chain D, Crystal Structure Of Human Atic In
Complex With Xmp
gi|47168534|pdb|1P4R|A Chain A, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor Bw1540u88ud
gi|47168535|pdb|1P4R|B Chain B, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor Bw1540u88ud
gi|48425206|pdb|1PL0|A Chain A, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor, Bw2315u89uc
gi|48425207|pdb|1PL0|B Chain B, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor, Bw2315u89uc
gi|48425208|pdb|1PL0|C Chain C, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor, Bw2315u89uc
gi|48425209|pdb|1PL0|D Chain D, Crystal Structure Of Human Atic In
Complex With Folate- Based Inhibitor, Bw2315u89uc
gi|1311462|dbj|BAA11559.1|
5-aminoimidazole-4-carboxamide-1-beta-D-ribonucl eotide
transformylase/inosinicase [Homo sapiens]
gi|2317692|dbj|BAA21762.1| 5-aminoimidazole-4-carboxamide
ribonucleotide transformylase [Homo sapiens]
gi|14250818|gb|AAH08879.1| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase [Homo
sapiens]
gi|21104440|dbj|BAB93490.1|
5-aminoimidazole-4-carboxamide-1-bata-D-ribonucl eotid
transformylase/inosinicase [Homo sapiens]
gi|1588260|prf||2208275A purH gene
Length = 592
Score = 672 bits (1735), Expect = 0.0
Identities = 356/642 (55%), Positives = 446/642 (69%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
LA+ SVSDKTGL+ A L + GL L+ASGGTAKA+RD G+ V DV+++T FPEMLGGRV
Sbjct: 6 LALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR+ D D+ + + + + VV CNLYPF KTV S +VEEAVE ID
Sbjct: 66 KTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISELKSG---GTTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+C+P DY + +E++S T+ E R+ LALKAF HT Y
Sbjct: 126 IGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQY 185
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
DE+IS + R++++ G +PLRYG NPHQ A+LY ++ ++PI VLNG+PG+IN+ D
Sbjct: 186 DEAISDYFRKQYS-KGVSQMPLRYGMNPHQTP-AQLYTLQPKLPITVLNGAPGFINLCDA 243
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLVKEL +A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P ++A
Sbjct: 244 LNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDL-YKTLTP-ISA 301
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG++AP
Sbjct: 302 AYARAR-----------------GADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAP 344
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL++L+KKKNGNYCVL+++ +Y P E E RT+FGL L QKRNN V++ F+NVV
Sbjct: 345 GYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVV 404
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ L + A+ DLIVATIA+KY QS
Sbjct: 405 TKNKD----------------------------------LPESALRDLIVATIAVKYTQS 430
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIG+GAGQQSRIHCTRLAGDKA WWLR HP VLS+ +K +KR+E SNA
Sbjct: 431 NSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNA 490
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID +G +G + + +W+ F E E L E ++K+W+ + T V +SSDAF PFRDNVD
Sbjct: 491 IDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDR 550
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV+Y+A P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 AKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 592
>gi|2541906|dbj|BAA22837.1| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase
[Rattus norvegicus]
Length = 592
Score = 671 bits (1731), Expect = 0.0
Identities = 358/642 (55%), Positives = 444/642 (68%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
LA+ SVSDKTGL+ A S GL+L+ASGGTAKAIRD G+ V DV+++T FPEMLGGRV
Sbjct: 6 LALFSVSDKTGLVEFARNHASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR+ D D+ + + + + VVVCNLYPF KTV S D +VE AVE ID
Sbjct: 66 KTLHPAVHAGILARNIPEDAADMARLDFNLIRVVVCNLYPFVKTVASPDVTVEAAVEQID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISELKSGG---TTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+C+P DY + +E++ G T+ E R+ LALKAF HT Y
Sbjct: 126 IGGVTLLRAAAKNHARVTVVCEPEDYGAVAAEMQGSGNKDTSLETRRHLALKAFTHTAQY 185
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
DE+IS + RR+++ G +PLRYG NPHQ A+LY ++ ++PI VLNG+PG+IN+ D
Sbjct: 186 DEAISDYFRRQYS-KGISQMPLRYGMNPHQ-TPAQLYTLKPKLPITVLNGAPGFINLCDA 243
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLV EL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P LA
Sbjct: 244 LNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDL-YPTLTP-LAI 301
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG+VAP
Sbjct: 302 AYARAR-----------------GADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAP 344
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL +L+KKKNG+YCVL+++ +Y P E E RT+FGLRL QKRNN V++ F+N+V
Sbjct: 345 GYEEEALKILSKKKNGSYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIV 404
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ L + A+ DLIVATIA+KY QS
Sbjct: 405 TKNKD----------------------------------LPESALRDLIVATIAVKYTQS 430
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR+E SNA
Sbjct: 431 NSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEVSNA 490
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID +G +G + +W+ F E E L E ++K+W+ + +GV +SSDAF PFRDNVD
Sbjct: 491 IDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDR 550
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV+Y+ P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 AKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH 592
>gi|37572276|gb|AAH39925.2| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase [Mus
musculus]
Length = 592
Score = 669 bits (1726), Expect = 0.0
Identities = 358/642 (55%), Positives = 443/642 (68%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
LA+ SVSDKTGL+ A L S GL+L+ASGGTAKAIRD G+ V DV+++T FPEMLGGRV
Sbjct: 6 LALFSVSDKTGLVEFARSLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR+ D D+ + + + V VVVCNLYPF KTV S D +VE AVE ID
Sbjct: 66 KTLHPAVHAGILARNIPEDAADMARLDFNLVRVVVCNLYPFVKTVASPDVTVEAAVEQID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISEL---KSGGTTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+C+P DY + +E+ S T+ E R+ LALKAF HT Y
Sbjct: 126 IGGVTLLRAAAKNHARVTVVCEPEDYAGVAAEMHGSDSKDTSLETRRHLALKAFTHTAQY 185
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
DE+IS + R++++ G +PLRYG NPHQ A+ Y ++ ++PI VLNG+PG+IN+ D
Sbjct: 186 DEAISDYFRKQYS-KGISQMPLRYGMNPHQ-TPAQSYTLKPKLPITVLNGAPGFINLCDA 243
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLV EL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P LA
Sbjct: 244 LNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDL-YPTLTP-LAV 301
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG+VAP
Sbjct: 302 AYARAR-----------------GADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAP 344
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL +L+KKKNGNYCVL+++ +Y P E E RT+FGLRL QKRNN V++ F+N+V
Sbjct: 345 GYEEEALKILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIV 404
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ L + A+ DLIVAT+A+KY QS
Sbjct: 405 TKNKD----------------------------------LPESALRDLIVATVAVKYTQS 430
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR+E SNA
Sbjct: 431 NSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEISNA 490
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID +G +G + +W+ F E E L E ++K+W+ + +GV +SSDAF PFRDNVD
Sbjct: 491 IDQYVTGTIGEGEDLVKWEALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDR 550
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV+Y+ P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 AKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH 592
>gi|27229048|ref|NP_080471.1| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase [Mus
musculus]
gi|15214215|sp|Q9CWJ9|PUR9_MOUSE Bifunctional purine biosynthesis
protein PURH [Includes:
Phosphoribosylaminoimidazolecarboxamide formyltransferase
(AICAR transformylase); IMP cyclohydrolase (Inosinicase)
(IMP synthetase) (ATIC)]
gi|12846177|dbj|BAB27060.1| unnamed protein product [Mus musculus]
Length = 592
Score = 668 bits (1723), Expect = 0.0
Identities = 358/642 (55%), Positives = 443/642 (68%), Gaps = 3/642 (0%)
Frame = +1
Query: 82 LAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRV 261
LA+ SVSDKTGL+ A L S GL+L+ASGGTAKAIRD G+ V DV+++T FPEMLGGRV
Sbjct: 6 LALFSVSDKTGLVEFARSLASLGLSLVASGGTAKAIRDAGLAVRDVSELTGFPEMLGGRV 65
Query: 262 KTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENID 441
KTLHPAVH GILAR+ D D+ + + + V VVVCNLYPF KTV S D +VE AVE ID
Sbjct: 66 KTLHPAVHAGILARNIPEDAADMARLDFNLVRVVVCNLYPFVKTVASPDVTVEAAVEQID 125
Query: 442 IGGVTLLRAAAKNHERVSVICDPADYDHIISEL---KSGGTTRERRQLLALKAFEHTTSY 612
IGGVTLLRAAAKNH RV+V+C+P DY + +E+ S T+ E R+ LALKAF HT Y
Sbjct: 126 IGGVTLLRAAAKNHARVTVVCEPEDYAGVAAEMHGSDSKDTSLETRRHLALKAFTHTAQY 185
Query: 613 DESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDG 792
DE+IS + R++++ G +PLRYG NPHQ A+LY ++ ++PI VLNG+PG+IN+ D
Sbjct: 186 DEAISDYFRKQYS-KGISQMPLRYGMNPHQ-TPAQLYTLKPKLPITVLNGAPGFINLCDA 243
Query: 793 LNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAA 972
LN WQLV EL A +PAAASFKHVSPAGAAVG+PL+E EA CMV DL T P LA
Sbjct: 244 LNAWQLVTELRGAVDIPAAASFKHVSPAGAAVGVPLSEDEARVCMVYDL-YPTLTP-LAV 301
Query: 973 AYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAP 1152
AYARAR GADRMSSFGDF+ALS+ CD TAKII+REVSDG+VAP
Sbjct: 302 AYARAR-----------------GADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAP 344
Query: 1153 DFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVV 1332
++ AL +L+KKKNGNYCVL+++ + P E E RT+FGLRL QKRNN V++ F+N+V
Sbjct: 345 GYEEEALKILSKKKNGNYCVLQMDQSCKPDENEVRTLFGLRLSQKRNNGVVDKSLFSNIV 404
Query: 1333 GSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQS 1512
+ L + A+ DLIVAT+A+KY QS
Sbjct: 405 TKNKD----------------------------------LPESALRDLIVATVAVKYTQS 430
Query: 1513 NSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNA 1692
NSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS+ +K +KR+E SNA
Sbjct: 431 NSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSMKFKAGVKRAEISNA 490
Query: 1693 IDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDC 1872
ID +G +G + +W+ F E E L E ++K+W+ + +GV +SSDAF PFRDNVD
Sbjct: 491 IDQYVTGTIGEGEDLVKWEALFEEVPELLTEAEKKEWVDKLSGVSVSSDAFFPFRDNVDR 550
Query: 1873 AKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
AK+ GV+Y+ P GS D + EACDE GI L HT LRLFHH
Sbjct: 551 AKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHTDLRLFHH 592
>gi|48734658|gb|AAH72321.1| Unknown (protein for IMAGE:6317471)
[Xenopus laevis]
Length = 593
Score = 667 bits (1720), Expect = 0.0
Identities = 358/651 (54%), Positives = 447/651 (67%), Gaps = 3/651 (0%)
Frame = +1
Query: 55 LCEMTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTK 234
L EM + +A+ SVSDK+GL+ A L + GL+L+ASGGTAK +RD G+ V DV+++T
Sbjct: 2 LAEMAE---IALFSVSDKSGLVEFAQQLSTLGLSLVASGGTAKCLRDAGLSVRDVSEITG 58
Query: 235 FPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCS 414
FPEMLGGRVKTLHPAVH GILAR + D+ D+ + S++ VVVCNLYPF KTV + +
Sbjct: 59 FPEMLGGRVKTLHPAVHAGILARSSPEDQADVSRLGFSYIRVVVCNLYPFVKTVSAAGVT 118
Query: 415 VEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKSG---GTTRERRQLLAL 585
VEEAVE IDIGGVTLLRAAAKNH RV+V+CDP+DY I E+ TT E R LAL
Sbjct: 119 VEEAVEQIDIGGVTLLRAAAKNHARVTVVCDPSDYKCIAEEMGKSDKKNTTPETRCQLAL 178
Query: 586 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 765
KAF HT YD++IS + R++++ G LPLRYG NPHQ A++Y ++P+ VLNGS
Sbjct: 179 KAFTHTAQYDDAISDYFRKQYS-KGISQLPLRYGINPHQV-PAQIYTRGPQLPLTVLNGS 236
Query: 766 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 945
PG+IN+ D LN WQLV+EL +A +PAA SFKHVSPAGAAVG+PL E EA CMV D+
Sbjct: 237 PGFINLCDALNAWQLVRELKNALGLPAATSFKHVSPAGAAVGVPLTEEEAQVCMVQDI-F 295
Query: 946 DTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINR 1125
T P LA AYARAR GADRMSSFGDFIA+S+ CD TAKII+R
Sbjct: 296 PTLTP-LATAYARAR-----------------GADRMSSFGDFIAVSDVCDVATAKIISR 337
Query: 1126 EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI 1305
EVSDG+VAP ++ AL +L+KKKNG+YCVL+++ +Y PS+ E R++FGL+L QKRNNAVI
Sbjct: 338 EVSDGIVAPGYEDEALKILSKKKNGSYCVLQMDLSYEPSDIEIRSLFGLQLEQKRNNAVI 397
Query: 1306 NAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA 1485
+ FNNVV + E+ + A+ DLIVA
Sbjct: 398 DRTLFNNVVTNNKEIPE----------------------------------SAVRDLIVA 423
Query: 1486 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNA 1665
TIALKY QSNSVC+A GQVIGMGAGQQSRIHCTRLAGDKA NWWLR HP VL + +K
Sbjct: 424 TIALKYTQSNSVCYAKDGQVIGMGAGQQSRIHCTRLAGDKADNWWLRHHPRVLGMKFKAG 483
Query: 1666 IKRSEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAF 1845
+KR+E SNAID SG LG E + QWQ ++EP E L +++ W+S+ +GV +SSDAF
Sbjct: 484 VKRAEISNAIDQYVSGTLGEE-DLPQWQALYDEPPEQLTLAEKRDWISKLSGVSLSSDAF 542
Query: 1846 LPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
PF+DN++ AK+ GV +A P GS D + +AC+E GI L HT LRLFHH
Sbjct: 543 FPFKDNLERAKKSGVQSIAAPSGSAADKVVIDACNELGIVLAHTNLRLFHH 593
>gi|14278285|pdb|1G8M|A Chain A, Crystal Structure Of Avian Atic, A
Bifunctional Transformylase And Cyclohydrolase Enzyme In
Purine Biosynthesis At 1.75 Ang. Resolution
gi|14278286|pdb|1G8M|B Chain B, Crystal Structure Of Avian Atic, A
Bifunctional Transformylase And Cyclohydrolase Enzyme In
Purine Biosynthesis At 1.75 Ang. Resolution
Length = 593
Score = 662 bits (1709), Expect = 0.0
Identities = 359/648 (55%), Positives = 437/648 (67%), Gaps = 3/648 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M + LA++SVS+K GL+ A L + GL LIASGGTA A+RD G+ V DV+D+T FPE
Sbjct: 1 MAARQQLALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPE 60
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
LGGRVKTLHPAVH GILAR+ D D K + S V VVVCNLYPF KTV S +V E
Sbjct: 61 XLGGRVKTLHPAVHAGILARNIPEDNADXNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPE 120
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISEL---KSGGTTRERRQLLALKAF 594
AVE IDIGGV LLRAAAKNH RV+V+CDPADY + E K T+ E R+ LALKAF
Sbjct: 121 AVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEXAASKDKDTSVETRRHLALKAF 180
Query: 595 EHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGY 774
HT YD +IS + R+ ++ G LPLRYG NPHQ A+LY ++P+ V+NGSPG+
Sbjct: 181 THTAQYDAAISDYFRKEYS-KGVSQLPLRYGXNPHQ-SPAQLYTTRPKLPLTVVNGSPGF 238
Query: 775 INILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTK 954
IN+ D LN WQLVKEL A +PAAASFKHVSPAGAAVG+PL+E EA C V DL T
Sbjct: 239 INLCDALNAWQLVKELKQALGIPAAASFKHVSPAGAAVGIPLSEEEAQVCXVHDLH-KTL 297
Query: 955 KPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVS 1134
P LA+AYAR+R GADR SSFGDFIALS+ CD TAKII+REVS
Sbjct: 298 TP-LASAYARSR-----------------GADRXSSFGDFIALSDICDVPTAKIISREVS 339
Query: 1135 DGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAE 1314
DGVVAP ++ AL +L+KKKNG YCVL+ +PNY P + E RT++GL+L QKRNNAVI+
Sbjct: 340 DGVVAPGYEEEALKILSKKKNGGYCVLQXDPNYEPDDNEIRTLYGLQLXQKRNNAVIDRS 399
Query: 1315 TFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIA 1494
F N+V + N+ L + A+ DLIVA+IA
Sbjct: 400 LFKNIV-TKNKT---------------------------------LPESAVRDLIVASIA 425
Query: 1495 LKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKR 1674
+KY QSNSVC+A GQVIG+GAGQQSRIHCTRLAGDKA +WWLR HP VLS +K +KR
Sbjct: 426 VKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANSWWLRHHPRVLSXKFKAGVKR 485
Query: 1675 SEKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPF 1854
+E SNAID +G +G + + +WQ F E L E ++KQW+++ T V +SSDAF PF
Sbjct: 486 AEVSNAIDQYVTGTIGEDEDLVKWQAXFEEVPAQLTEAEKKQWIAKLTAVSLSSDAFFPF 545
Query: 1855 RDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
RDNVD AK+ GV ++ P GS D+ + EAC+E GITLIHT LRLFHH
Sbjct: 546 RDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH 593
>gi|31242553|ref|XP_321707.1| ENSANGP00000015783 [Anopheles gambiae]
gi|21289473|gb|EAA01766.1| ENSANGP00000015783 [Anopheles gambiae str.
PEST]
Length = 640
Score = 660 bits (1703), Expect = 0.0
Identities = 347/646 (53%), Positives = 441/646 (67%), Gaps = 1/646 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M GK +A++SVSDK+GL+ A GL GL L+ASGGTAKAIRD G+ V DV+D+T PE
Sbjct: 51 MASGK-IALVSVSDKSGLVEFAKGLNELGLKLVASGGTAKAIRDLGLPVRDVSDITGAPE 109
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
MLGGRVKTLHPAVH ILAR TESD++D+ + +VVCNLYPF T+ D ++ +
Sbjct: 110 MLGGRVKTLHPAVHAAILARMTESDQRDISQQKYELAQLVVCNLYPFGLTISKPDVTIAD 169
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKS-GGTTRERRQLLALKAFEH 600
AVENIDIGGVTLLRAAAKNH+RV+V+CDP DY ++ E++ G TT RQLLALKAF H
Sbjct: 170 AVENIDIGGVTLLRAAAKNHQRVTVLCDPKDYPKVLEEIRQHGDTTPATRQLLALKAFTH 229
Query: 601 TTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYIN 780
T YD IS + R++++ G L LRYG NPHQK A+++ + + +P+KV+N SPG+IN
Sbjct: 230 TAEYDAIISDYFRKQYSA-GVSQLNLRYGMNPHQK-PAQIFTLLERLPLKVVNASPGFIN 287
Query: 781 ILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKP 960
+ D LNGWQLV+EL A +PAA SFKHVSPAGAAVG+ L+ +A CMV D+ +D+ P
Sbjct: 288 LCDALNGWQLVRELKRALGLPAATSFKHVSPAGAAVGVALSLEQAKLCMVDDM-MDSLTP 346
Query: 961 SLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDG 1140
+A AYARAR GADRMSSFGDF+ALS+ CD TAKII REVSDG
Sbjct: 347 -MATAYARAR-----------------GADRMSSFGDFVALSDTCDLATAKIIAREVSDG 388
Query: 1141 VVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETF 1320
++AP + AL +L KKKNG+YCVL+I+P Y P E +T+FGL+L Q+RN+A IN F
Sbjct: 389 IIAPGYTEEALEVLRKKKNGSYCVLQIDPTYEPGPVERKTLFGLQLEQRRNDADINKALF 448
Query: 1321 NNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALK 1500
N+V + N+ L + A+ DLIVATIALK
Sbjct: 449 TNIV-TKNKT---------------------------------LPEGALRDLIVATIALK 474
Query: 1501 YAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSE 1680
Y QSNSVC+A GQV+G+GAGQQSRIHCTRLAGDKA NWWLRQHP V + ++ +KR+E
Sbjct: 475 YTQSNSVCYAKDGQVVGIGAGQQSRIHCTRLAGDKADNWWLRQHPRVAGMQFRKGVKRAE 534
Query: 1681 KSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRD 1860
SNAID +G +G ++ + Q++ + PL +D++QW Q TGV + SDAF PFRD
Sbjct: 535 ISNAIDNYVNGTVGKDMPVAQFEAMLEKVPAPLTGEDKEQWTRQLTGVSLGSDAFFPFRD 594
Query: 1861 NVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
NVD AK GVSY+A P GS D + +AC+EH I ++HT LRLFHH
Sbjct: 595 NVDRAKLSGVSYIASPAGSTNDAGVIDACNEHDIVMVHTNLRLFHH 640
>gi|34305305|gb|AAQ63487.1| 5-aminoimidazole-4-carboxamide
ribonucleotide formyltransferase/IMP cyclohydrolase
[Leptinotarsa decemlineata]
Length = 594
Score = 651 bits (1679), Expect = 0.0
Identities = 340/647 (52%), Positives = 443/647 (67%), Gaps = 3/647 (0%)
Frame = +1
Query: 67 TDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEM 246
T+ +A++SVSDK GL+ + L + G TL+ SGGTA +R G+ + DV++++ PE+
Sbjct: 3 TNSGKIALLSVSDKIGLVDIGKKLHTLGFTLVGSGGTAAILRGAGLPIKDVSEISGAPEI 62
Query: 247 LGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEA 426
LGGRVKTLHPAVHGGILAR SD++DL K NI + +V+CNLYPFK+TV +D ++ +A
Sbjct: 63 LGGRVKTLHPAVHGGILARLQPSDQEDLRKQNIEMIRIVICNLYPFKETVSKEDVTLSDA 122
Query: 427 VENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKS---GGTTRERRQLLALKAFE 597
VENIDIGGVTLLRAAAKNHERV+V+ DPADY+ I+ E++S TT E R+ LALKAF
Sbjct: 123 VENIDIGGVTLLRAAAKNHERVTVVVDPADYNKILQEIRSSPNNDTTIETRRTLALKAFT 182
Query: 598 HTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYI 777
HT YD +IS + R+ F+ N + L LRYG NPHQK A+LY +++P+ V+NGSPG+I
Sbjct: 183 HTCQYDLAISDYFRKEFSQN-QSQLSLRYGMNPHQK-PAQLYTTLEKLPLTVVNGSPGFI 240
Query: 778 NILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKK 957
N+ D LN WQLVKEL +PAA SFKHVSPAGAAVG+PL+ +A CMV D+ ++
Sbjct: 241 NLCDALNSWQLVKELKTVIGLPAATSFKHVSPAGAAVGIPLDHNQAKLCMVDDI-LEELS 299
Query: 958 PSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSD 1137
P LA AYARAR GADRMSSFGDF+ALS+ CD TA++I+REVSD
Sbjct: 300 P-LAIAYARAR-----------------GADRMSSFGDFVALSDICDHPTARLISREVSD 341
Query: 1138 GVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAET 1317
GV+AP + P AL LL KK+NGNY VL+I+PNY P+ E + +FGL L Q+RN+A+I+
Sbjct: 342 GVIAPGYTPEALELLRKKENGNYSVLQIDPNYNPNPIETKVIFGLTLEQRRNDALIDKSL 401
Query: 1318 FNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIAL 1497
F N+ VSD ++L + A+ DLIVATIAL
Sbjct: 402 FKNI------VSDNKNLP----------------------------EDAVRDLIVATIAL 427
Query: 1498 KYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRS 1677
KY QSNSVC+A GQV+G+GAGQQSRIHCTRLAGDKA NWW+RQHP VL + ++ +KR+
Sbjct: 428 KYTQSNSVCYAKDGQVVGIGAGQQSRIHCTRLAGDKADNWWMRQHPKVLGMKFRKGVKRA 487
Query: 1678 EKSNAIDVLCSGVLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFR 1857
E SNAID +G +G ++ ++ ++ +E +R+ WLSQ GV ++SDAF PFR
Sbjct: 488 EISNAIDNFVNGSVGKDMDRSIFESMYDVVPIEFSETERRTWLSQLKGVALASDAFFPFR 547
Query: 1858 DNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
DNVD A+ GVSY+ P GS D+++ AC+EH I L HT LRLFHH
Sbjct: 548 DNVDRARLSGVSYIGCPSGSTNDEEVVRACNEHKIVLAHTNLRLFHH 594
>gi|7498000|pir||T29605 hypothetical protein C55F2.1 - Caenorhabditis
elegans
Length = 371
Score = 645 bits (1663), Expect = 0.0
Identities = 327/344 (95%), Positives = 327/344 (95%)
Frame = +1
Query: 586 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 765
KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS
Sbjct: 45 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 104
Query: 766 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 945
PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI
Sbjct: 105 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 164
Query: 946 DTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINR 1125
DTKKPSLAAAYARAR GADRMSSFGDFIALSEKCDELTAKIINR
Sbjct: 165 DTKKPSLAAAYARAR-----------------GADRMSSFGDFIALSEKCDELTAKIINR 207
Query: 1126 EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI 1305
EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI
Sbjct: 208 EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI 267
Query: 1306 NAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA 1485
NAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA
Sbjct: 268 NAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA 327
Query: 1486 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNW 1617
TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNW
Sbjct: 328 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNW 371
>gi|46439064|gb|EAK98386.1| hypothetical protein CaO19.492 [Candida
albicans SC5314]
gi|46439157|gb|EAK98478.1| hypothetical protein CaO19.8122 [Candida
albicans SC5314]
Length = 592
Score = 643 bits (1658), Expect = 0.0
Identities = 349/639 (54%), Positives = 420/639 (65%), Gaps = 1/639 (0%)
Frame = +1
Query: 85 AIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRVK 264
AI+SV DKTGL+ LA GLV+A + ++ASGGTAK IR+ G V DV+ +T PEMLGGRVK
Sbjct: 10 AILSVYDKTGLLDLAKGLVAANVRILASGGTAKLIREAGFPVEDVSSITHAPEMLGGRVK 69
Query: 265 TLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENIDI 444
TLHPAVHGGILAR+ ESD DL I V VVCNLYPFK+T+ +V EAVE IDI
Sbjct: 70 TLHPAVHGGILARNLESDEHDLTAQGIEKVDFVVCNLYPFKETISKVAVTVPEAVEEIDI 129
Query: 445 GGVTLLRAAAKNHERVSVICDPADYDHIISELKSGGTTRERRQLLALKAFEHTTSYDESI 624
GGVTLLRAAAKNHERVS++ DP DY H + ELKSG T E R LALKAFEHT YD +I
Sbjct: 130 GGVTLLRAAAKNHERVSILSDPQDYAHFLEELKSGEITAETRNRLALKAFEHTADYDVAI 189
Query: 625 SGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDGLNGW 804
S F R+++A N + LPLRYG NPHQK A+ ++ E E+P KVLNGSPGYIN+LD LN W
Sbjct: 190 SDFFRKQYAENISQ-LPLRYGANPHQK-PAQAFVSEGELPFKVLNGSPGYINLLDALNSW 247
Query: 805 QLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAAAYAR 984
LVKELS + +PAAASFKHVSPAGAAVGLPL + E V D I+ P LA AYAR
Sbjct: 248 PLVKELSASLNLPAAASFKHVSPAGAAVGLPLTDIEKKIYFVED--IENLSP-LANAYAR 304
Query: 985 AREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAPDFDP 1164
AR GADRMSSFGDFIALS D+ TA+II++EVSDGV+AP +
Sbjct: 305 AR-----------------GADRMSSFGDFIALSNIVDKPTAQIISKEVSDGVIAPGYSE 347
Query: 1165 AALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVVGSAN 1344
AL LL KKKNG YC+L+I+PNY P E R V+G+ L+QKRN+A+ +F +V
Sbjct: 348 EALELLKKKKNGKYCILQIDPNYNPENLESRQVYGITLQQKRNDAIFKGSSFKEIVSKNK 407
Query: 1345 EVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQSNSVC 1524
+ L +Q DL +ATIALKY QSNSVC
Sbjct: 408 D----------------------------------LTEQGAVDLTIATIALKYTQSNSVC 433
Query: 1525 FAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNAIDVL 1704
+A G VIG+GAGQQSRIHCTRLAGDKA NWWLRQHP VL W KR EKSNAID+
Sbjct: 434 YAKNGMVIGLGAGQQSRIHCTRLAGDKADNWWLRQHPKVLGFKWAKGTKRPEKSNAIDLY 493
Query: 1705 CSGVLGS-EIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDCAKQ 1881
+ + + E +++ F E EPL ++RK+WLS+ + V +SSDAF PF DNV A +
Sbjct: 494 VTNQIPTEEPEKSEYESKFAEIPEPLTAEERKEWLSKLSNVALSSDAFFPFPDNVYRAAR 553
Query: 1882 FGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
GV ++A P GSV D + A D + I + +RLFHH
Sbjct: 554 SGVKFIAAPSGSVMDKAVFAAADANDIVYVENPIRLFHH 592
>gi|6323768|ref|NP_013839.1| Enzyme of 'de novo' purine biosynthesis
containing both 5-aminoimidazole-4-carboxamide
ribonucleotide transformylase and inosine monophosphate
cyclohydrolase activities, isozyme of Ade16p; ade16 ade17
mutants require adenine and histidine; Ade17p
[Saccharomyces cerevisiae]
gi|1709915|sp|P38009|PU92_YEAST Bifunctional purine biosynthesis
protein ADE17 [Includes:
Phosphoribosylaminoimidazolecarboxamide formyltransferase
(AICAR transformylase); IMP cyclohydrolase (Inosinicase)
(IMP synthetase) (ATIC)]
gi|1084913|pir||S54489 phosphoribosylaminoimidazolecarboxamide
formyltransferase (EC 2.1.2.3) - yeast (Saccharomyces
cerevisiae)
gi|809579|emb|CAA89269.1| unknown [Saccharomyces cerevisiae]
Length = 592
Score = 640 bits (1650), Expect = 0.0
Identities = 342/647 (52%), Positives = 428/647 (65%), Gaps = 2/647 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M + AI+SV DKTGL+ LA GL+ + ++ASGGTA+ IRD G + DV+ +T PE
Sbjct: 1 MANYTKTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRDAGFPIEDVSAITHAPE 60
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
MLGGRVKTLHPAVHGGILARD +SD KDL++ +I V VVCNLYPFK+TV ++ E
Sbjct: 61 MLGGRVKTLHPAVHGGILARDIDSDEKDLKEQHIEKVDYVVCNLYPFKETVAKVGVTIPE 120
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKSGG-TTRERRQLLALKAFEH 600
AVE IDIGGVTLLRAAAKNH RV+++ DP DY +SEL S G +++ R LALKAFEH
Sbjct: 121 AVEEIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELSSNGEISQDLRNRLALKAFEH 180
Query: 601 TTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYIN 780
T YD +IS F R++++ G+ + LRYG NPHQK +D +P KVL GSPGYIN
Sbjct: 181 TADYDAAISDFFRKQYS-EGQAQITLRYGANPHQKPAQAYVSQQDSLPFKVLCGSPGYIN 239
Query: 781 ILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKP 960
+LD LN W LVKELS + +PAAASFKHVSPAGAAVG+PL++ E V+D I+ P
Sbjct: 240 LLDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVGIPLSDVEKQVYFVAD--IENLSP 297
Query: 961 SLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDG 1140
LA AYARAR GADRMSSFGD+IALS D TAKII+REVSDG
Sbjct: 298 -LACAYARAR-----------------GADRMSSFGDWIALSNIVDVPTAKIISREVSDG 339
Query: 1141 VVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETF 1320
V+AP ++P AL++L+KKK G YC+L+I+PNY+P E R V+G+ L QKRN+A+IN TF
Sbjct: 340 VIAPGYEPEALAILSKKKGGKYCILQIDPNYVPEAVERRQVYGVTLEQKRNDAIINQSTF 399
Query: 1321 NNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALK 1500
+V S N+ L +QAI DL VATIA+K
Sbjct: 400 KEIV-SQNK---------------------------------NLTEQAIIDLTVATIAIK 425
Query: 1501 YAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSE 1680
Y QSNSVC+A G V+G+GAGQQSRIHCTRLAGDKA NWW RQHP VL + W +KR E
Sbjct: 426 YTQSNSVCYARNGMVVGLGAGQQSRIHCTRLAGDKADNWWFRQHPRVLEIKWAKGVKRPE 485
Query: 1681 KSNAIDVLCSGVLGS-EIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFR 1857
KSNAID+ +G + + E + ++Q F E +P ++RK+WLS+ T V +SSDAF PF
Sbjct: 486 KSNAIDLFVTGQIPTEEPELSEYQSKFEEIPKPFTPEERKEWLSKLTNVSLSSDAFFPFP 545
Query: 1858 DNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
DNV A + GV Y+A P GSV D + A D + + +RLFHH
Sbjct: 546 DNVYRAVKSGVKYIAAPSGSVMDKVVFSAADSFDLVYVENPIRLFHH 592
>gi|50551513|ref|XP_503230.1| hypothetical protein [Yarrowia
lipolytica]
gi|49649098|emb|CAG81431.1| unnamed protein product [Yarrowia
lipolytica CLIB99]
Length = 590
Score = 640 bits (1650), Expect = 0.0
Identities = 346/646 (53%), Positives = 430/646 (66%), Gaps = 1/646 (0%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M++ + +AI+SV DKTGL+ LA GLV + L+ASGGTAK +R+ G V DV+ +T PE
Sbjct: 1 MSERQKIAILSVYDKTGLLDLAKGLVKNNVRLLASGGTAKLVREAGFPVEDVSAITHAPE 60
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
ML GRVKTLHPAVHGGILAR+ ESD KDL I V VVCNLYPF+ TV + ++EE
Sbjct: 61 MLSGRVKTLHPAVHGGILARNIESDEKDLSAQGIDKVDFVVCNLYPFQDTVAKINVTIEE 120
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKSGGTTRERRQLLALKAFEHT 603
AVE IDIGGVTLLRAAAKNH RV+++ DP DY ++EL G + E R LALKAFEHT
Sbjct: 121 AVEEIDIGGVTLLRAAAKNHSRVTILSDPRDYHAFLNELDHGAISAETRNRLALKAFEHT 180
Query: 604 TSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINI 783
YD +IS F R++++ + + +PLRYG NPHQK A+ ++ + E+P KVL GSPGYIN+
Sbjct: 181 ADYDSAISDFFRKQYSEDLSQ-MPLRYGANPHQKP-AQAFVQQGELPFKVLCGSPGYINL 238
Query: 784 LDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPS 963
LD LN W LVKELS + +PAAASFKHVSPAGAAVGLPL++ E V D I+ P
Sbjct: 239 LDALNSWPLVKELSASLNLPAAASFKHVSPAGAAVGLPLSDIEKKIYFVED--IENLSP- 295
Query: 964 LAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGV 1143
LA AYARAR GADRMSSFGDFIALS D TA+II++EVSDGV
Sbjct: 296 LANAYARAR-----------------GADRMSSFGDFIALSNIVDLPTAQIISKEVSDGV 338
Query: 1144 VAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFN 1323
+AP ++P AL LL KKK G YCVL+I+PN+ P E R V+G+ L+QKRN+AVI++ +F
Sbjct: 339 IAPGYEPEALELLKKKKGGKYCVLQIDPNFTPGPVETRQVYGISLQQKRNDAVISSNSFK 398
Query: 1324 NVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKY 1503
+V E L +QAI DL VATIALKY
Sbjct: 399 ELVSKNKE----------------------------------LPEQAIIDLTVATIALKY 424
Query: 1504 AQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEK 1683
QSNSVC+A G VIG+GAGQQSRIHCTRLAGDKA NWW RQHP VL+ WK KR +K
Sbjct: 425 TQSNSVCYAKDGMVIGLGAGQQSRIHCTRLAGDKADNWWFRQHPKVLAFKWKKGTKRPDK 484
Query: 1684 SNAIDVLCSG-VLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRD 1860
SNAID+ SG + S + ++++ F EPL ++RK+WL + T V +SSDAF PF D
Sbjct: 485 SNAIDLYVSGQIPQSGVEKEEYEAKFETVPEPLTAEERKEWLGKLTKVALSSDAFFPFPD 544
Query: 1861 NVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
NV A + GVSY++ P GSV+D+ + A D GI + +RLFHH
Sbjct: 545 NVYRAARSGVSYISAPSGSVQDEAVFAAADSFGIAYVENNIRLFHH 590
>gi|50311693|ref|XP_455873.1| unnamed protein product [Kluyveromyces
lactis]
gi|49645009|emb|CAG98581.1| unnamed protein product [Kluyveromyces
lactis NRRL Y-1140]
Length = 590
Score = 639 bits (1649), Expect = 0.0
Identities = 341/639 (53%), Positives = 421/639 (65%), Gaps = 1/639 (0%)
Frame = +1
Query: 85 AIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPEMLGGRVK 264
AI+SV DKTGL+ LA GL + ++ASGGTAK +R+ G V DV+ +T PEMLGGRVK
Sbjct: 7 AILSVYDKTGLLDLAKGLAENNVRILASGGTAKMVREAGFPVDDVSSITHAPEMLGGRVK 66
Query: 265 TLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEEAVENIDI 444
TLHPAVHGGILAR+ ESD KDL++ NI V VVCNLYPFK+TV S+ EAVE IDI
Sbjct: 67 TLHPAVHGGILARNLESDEKDLKEQNIDKVDFVVCNLYPFKETVAKVGVSIPEAVEEIDI 126
Query: 445 GGVTLLRAAAKNHERVSVICDPADYDHIISELKSGGTTRERRQLLALKAFEHTTSYDESI 624
GGVTLLRAAAKNH RV+++ DP DY ++EL+ G + + R LALKAFEHT YD +I
Sbjct: 127 GGVTLLRAAAKNHARVTILSDPKDYPQFLNELQKGEISSDLRNTLALKAFEHTADYDTAI 186
Query: 625 SGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSPGYINILDGLNGW 804
S F R++++ N + L LRYG NPHQK ++E+P KVL+GSPGYIN+LD LN W
Sbjct: 187 SDFFRKQYSEN-KTQLALRYGANPHQKPAQAFVTQQEELPFKVLSGSPGYINLLDALNSW 245
Query: 805 QLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPIDTKKPSLAAAYAR 984
LVKELS + +PAAASFKHVSPAGAAVGLPL++ E V+D I+ P LA AYAR
Sbjct: 246 PLVKELSASLNLPAAASFKHVSPAGAAVGLPLSDVEKQIYFVAD--IENLSP-LACAYAR 302
Query: 985 AREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINREVSDGVVAPDFDP 1164
AR GADRMSSFGD+IALS D TAKII+REVSDGV+AP F+P
Sbjct: 303 AR-----------------GADRMSSFGDWIALSNIVDVPTAKIISREVSDGVIAPGFEP 345
Query: 1165 AALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVINAETFNNVVGSAN 1344
AL +L KKKNG YC+L+I+PNY P E R V+G+ L+QKRN+A+IN +F +V
Sbjct: 346 EALEILKKKKNGKYCILQIDPNYTPEALESRQVYGVTLQQKRNDAIINKSSFKEIVSQNK 405
Query: 1345 EVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVATIALKYAQSNSVC 1524
+ L +QA+ DL VATIALKY QSNSVC
Sbjct: 406 D----------------------------------LPEQAVIDLTVATIALKYTQSNSVC 431
Query: 1525 FAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNAIKRSEKSNAIDVL 1704
+A G V+G+GAGQQSRIHCTRLAGDKA NWWLRQHP VL W +KR EKSNAID+
Sbjct: 432 YAKNGMVVGLGAGQQSRIHCTRLAGDKADNWWLRQHPRVLGFKWAKGVKRPEKSNAIDLF 491
Query: 1705 CSGVLGS-EIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDAFLPFRDNVDCAKQ 1881
+G + + E +++ F EPL +++K W+S+ T V +SSDAF PF DNV A +
Sbjct: 492 VTGQIPTEEPEKSEYESKFETIPEPLTAEEKKSWMSKLTNVALSSDAFFPFPDNVYRAVR 551
Query: 1882 FGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
GV Y+A P GSV D + A D + + +RLFHH
Sbjct: 552 SGVKYIAAPSGSVMDKAVFGAADSFDLVYVENPIRLFHH 590
>gi|49094280|ref|XP_408601.1| hypothetical protein AN4464.2
[Aspergillus nidulans FGSC A4]
gi|40741039|gb|EAA60229.1| hypothetical protein AN4464.2 [Aspergillus
nidulans FGSC A4]
Length = 600
Score = 636 bits (1641), Expect = 0.0
Identities = 345/652 (52%), Positives = 433/652 (65%), Gaps = 7/652 (1%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGI-----DVHDVADV 228
M+ KS AI+SV DKTGL+ LA GL + L+ASGGTA+ IR+ G D+ DV+ +
Sbjct: 1 MSQQKS-AILSVYDKTGLLDLAKGLAKHNVRLLASGGTARMIREAGFPVELTDIRDVSAI 59
Query: 229 TKFPEMLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKD 408
T PEMLGGRVKTLHPAVHGGILARD ESD KDL NI+ V VVCNLYPFK+TV +
Sbjct: 60 THAPEMLGGRVKTLHPAVHGGILARDIESDEKDLADQNIAKVDFVVCNLYPFKETVNKVN 119
Query: 409 CSVEEAVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKSGGTTRERRQLLALK 588
++EEAVE IDIGGVTLLRAAAKNH RV+++ DP DY + EL++G T R+ ALK
Sbjct: 120 VTIEEAVEEIDIGGVTLLRAAAKNHSRVTILSDPQDYPEFLKELEAGEITETSRRSYALK 179
Query: 589 AFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGSP 768
AFEHT YD +ISGF R+++AGNGE+ L LRYGTNPHQK A + + ++P K LNGSP
Sbjct: 180 AFEHTADYDTAISGFFRKQYAGNGEKHLSLRYGTNPHQK-PASACMPQGKLPFKALNGSP 238
Query: 769 GYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPID 948
GY+N+LD LN W LVKEL A PAAASFKHVSPAGAAVG+PL++ E MV D+
Sbjct: 239 GYVNLLDALNAWALVKELKQALGYPAAASFKHVSPAGAAVGVPLSDKERKVYMVDDI-AG 297
Query: 949 TKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINRE 1128
+ LA AYARAR GADRMSSFGD +ALS+ D TAKII+RE
Sbjct: 298 IESSGLAQAYARAR-----------------GADRMSSFGDVLALSDVVDVTTAKIISRE 340
Query: 1129 VSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVIN 1308
VSDGV+AP ++ AL +L+KKK G Y VL+++ +Y+P+ E RTV+G++L Q RN+ VI+
Sbjct: 341 VSDGVIAPGYEKEALEILSKKKGGKYLVLQMDDSYVPAGEETRTVYGVQLNQHRNDVVIS 400
Query: 1309 -AETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA 1485
++TFN ++ K L L A+ DL VA
Sbjct: 401 PSKTFNTII--------------------------------TPKDLKTLPDAALRDLTVA 428
Query: 1486 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNA 1665
TIALKY QSNSVC+A GQV+G+GAGQQSRIHCTRLAGDK NWW+R H VL++ WK
Sbjct: 429 TIALKYTQSNSVCYALNGQVVGLGAGQQSRIHCTRLAGDKTDNWWMRFHERVLNIKWKAG 488
Query: 1666 IKRSEKSNAIDVLCSG-VLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQQTGVVMSSDA 1842
KR++KSNAID+LCSG +EI ++++ F E P +++R+ WL Q + V +SSDA
Sbjct: 489 TKRADKSNAIDLLCSGQTPRNEIEQAEYERVFEEVPAPFTQEERESWLKQLSEVAVSSDA 548
Query: 1843 FLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLFHH 1998
F PF DNV A + GV Y+A P GS D + E ++ GIT + G RLFHH
Sbjct: 549 FFPFIDNVFRAARSGVKYIAAPSGSQNDGPVFETAEKLGITFVEQGTRLFHH 600
>gi|50260232|gb|EAL22891.1| hypothetical protein CNBA6600
[Cryptococcus neoformans var. neoformans B-3501A]
Length = 605
Score = 635 bits (1639), Expect = 0.0
Identities = 348/662 (52%), Positives = 438/662 (65%), Gaps = 17/662 (2%)
Frame = +1
Query: 64 MTDGKSLAIISVSDKTGLIPLAHGLVSAGLTLIASGGTAKAIRDQGIDVHDVADVTKFPE 243
M+ +A++SV DKTGL+P A L G L+ SGGTAK IR+ G+++ DV+++TK PE
Sbjct: 1 MSSEAPIALLSVYDKTGLLPFAKSLKELGFRLLGSGGTAKMIREAGMEIEDVSNITKAPE 60
Query: 244 MLGGRVKTLHPAVHGGILARDTESDRKDLEKHNISFVSVVVCNLYPFKKTVQSKDCSVEE 423
MLGGRVKTLHPAVHGGIL+RD SD DL + IS +++VVCNLYPF DC++
Sbjct: 61 MLGGRVKTLHPAVHGGILSRDIPSDLADLATNKISPITLVVCNLYPFVLQTSKPDCTLAG 120
Query: 424 AVENIDIGGVTLLRAAAKNHERVSVICDPADYDHIISELKS-GGTTRERRQLLALKAFEH 600
A+E IDIGGVTLLRAAAKNH RVS+I P+DY+ I++ELK+ G + E ++ LA+KAFE
Sbjct: 121 AIEEIDIGGVTLLRAAAKNHGRVSIISSPSDYETIVAELKAKGEVSAETKRGLAIKAFED 180
Query: 601 TTSYDESISGFMRRRF------------AGNGERALPLRYGTNPHQKDDAELYIVEDEMP 744
T SYDE+IS + R+ + AG G + L LRYG NPHQK A+ ++ + EMP
Sbjct: 181 TKSYDEAISDYFRKVYATPGVEDEMKAGAGVGYQRLGLRYGANPHQK-PAQAFVEQGEMP 239
Query: 745 IKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACC 924
IKVL+GSPGYIN+LD LN W LVKEL+ +PAAASFKHVSPAGAAVGLPL+E A
Sbjct: 240 IKVLSGSPGYINLLDALNSWALVKELAAGLNLPAAASFKHVSPAGAAVGLPLDERAAKVF 299
Query: 925 MVSDLPIDTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDEL 1104
V DL + LA AYARAR GADRMSSFGDFIALS D
Sbjct: 300 GVEDL---KELSPLACAYARAR-----------------GADRMSSFGDFIALSHSVDTP 339
Query: 1105 TAKIINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQ 1284
TAKII+REVSDGV+AP ++P AL +L+KKK G YCVL+++PNY+P E E R V+G+ L+Q
Sbjct: 340 TAKIISREVSDGVIAPGYEPEALEILSKKKGGKYCVLQMDPNYVPPEIETRQVYGISLQQ 399
Query: 1285 KRNNAVINAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQA 1464
KRN+ I+ F NVV +AN+ L K A
Sbjct: 400 KRNDCKIDESLFRNVV-TANK---------------------------------DLPKSA 425
Query: 1465 IDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVL 1644
I DL+VAT+ALKY QSNSVC+A G VIG+GAGQQSRIHCTRLAGDKA NWWLR HP VL
Sbjct: 426 ITDLVVATLALKYTQSNSVCYALNGTVIGLGAGQQSRIHCTRLAGDKADNWWLRHHPRVL 485
Query: 1645 SLPWKNAIKRSEKSNAIDVLCSG----VLGSEIAIDQWQQYFNEPVEPLAEDDRKQWLSQ 1812
LP+K KR++K+NAID+ +G G E A QW+ F EPL +++R++ + +
Sbjct: 486 ELPFKKGTKRADKANAIDLFVTGQAFEAEGGERA--QWESLFETVPEPLTKEEREKHMKE 543
Query: 1813 QTGVVMSSDAFLPFRDNVDCAKQFGVSYVAHPGGSVRDDDIKEACDEHGITLIHTGLRLF 1992
TGV +SDAF PF DNV AK+ G +Y+A P GS+ D + +A DE+ + HT LRLF
Sbjct: 544 LTGVACASDAFFPFPDNVHRAKRSGATYLAAPSGSIMDKECIKAADENNLVFCHTDLRLF 603
Query: 1993 HH 1998
HH
Sbjct: 604 HH 605
>gi|37515243|gb|AAQ91905.1| Hypothetical protein C55F2.1c
[Caenorhabditis elegans]
Length = 393
Score = 635 bits (1639), Expect = 0.0
Identities = 330/382 (86%), Positives = 331/382 (86%)
Frame = +1
Query: 586 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 765
KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS
Sbjct: 45 KAFEHTTSYDESISGFMRRRFAGNGERALPLRYGTNPHQKDDAELYIVEDEMPIKVLNGS 104
Query: 766 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 945
PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI
Sbjct: 105 PGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAAVGLPLNETEAACCMVSDLPI 164
Query: 946 DTKKPSLAAAYARAREQDWMIADRLQRIAPSIGADRMSSFGDFIALSEKCDELTAKIINR 1125
DTKKPSLAAAYARAR GADRMSSFGDFIALSEKCDELTAKIINR
Sbjct: 165 DTKKPSLAAAYARAR-----------------GADRMSSFGDFIALSEKCDELTAKIINR 207
Query: 1126 EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI 1305
EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI
Sbjct: 208 EVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSETEERTVFGLRLRQKRNNAVI 267
Query: 1306 NAETFNNVVGSANEVSDIRSLQIFKKHFMLSFLQNFHKYNCIKKSLFQLNKQAIDDLIVA 1485
NAETFNNVVGSANE LNKQAIDDLIVA
Sbjct: 268 NAETFNNVVGSANE----------------------------------LNKQAIDDLIVA 293
Query: 1486 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNA 1665
TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNA
Sbjct: 294 TIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLSLPWKNA 353
Query: 1666 IKRSEKSNAIDVLCSGVLGSEI 1731
IKRSEKSNAIDVLCSGVLGSE+
Sbjct: 354 IKRSEKSNAIDVLCSGVLGSEV 375