Homology by BLASTX


BLASTX 2.2.4 [Aug-26-2002]
Query= C16A3_1
         (4314 letters)

Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
           1,967,186 sequences; 661,712,633 total letters


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17552208|ref|NP_498392.1| tho2 (164.4 kD) (3H463) [Caenorhabd...  2472   0.0
gi|25395798|pir||G88480 protein C16A3.7 [imported] - Caenorhabdi...  2032   0.0
gi|39584988|emb|CAE64412.1| Hypothetical protein CBG09105 [Caeno...  1985   0.0
gi|49619103|gb|AAT68136.1| Tho2 [Danio rerio]                         677   0.0
gi|50745998|ref|XP_420332.1| PREDICTED: similar to THO complex s...   672   0.0
gi|47222567|emb|CAG02932.1| unnamed protein product [Tetraodon n...   671   0.0
gi|37546516|ref|XP_047325.4| Tho2 [Homo sapiens]                      668   0.0
gi|41702296|sp|Q8NI27|THO2_HUMAN THO complex subunit 2 (Tho2) >g...   665   0.0
gi|34876073|ref|XP_223180.2| similar to Tho2 [Rattus norvegicus]      661   0.0
gi|38080348|ref|XP_144450.2| similar to Tho2 [Mus musculus]           656   0.0
gi|31222868|ref|XP_317233.1| ENSANGP00000011945 [Anopheles gambi...   637   0.0
gi|34932840|ref|XP_233081.2| similar to Tho2 [Rattus norvegicus]      629   e-178
gi|24581012|ref|NP_722763.1| CG31671-PA [Drosophila melanogaster...   625   e-177
gi|27802720|emb|CAD60810.1| SI:bZ1O18.2 (novel protein similar t...   563   e-158
gi|38086124|ref|XP_356322.1| similar to Tho2 [Mus musculus]           433   e-119
gi|9945085|gb|AAG03122.1| F5A9.21 [Arabidopsis thaliana]              420   e-115
gi|42562307|ref|NP_173871.3| expressed protein [Arabidopsis thal...   420   e-115
gi|34906976|ref|NP_914835.1| P0413C03.11 [Oryza sativa (japonica...   415   e-114
gi|48142235|ref|XP_393587.1| similar to THO complex subunit 2 (T...   387   e-105
gi|19862882|sp|Q09779|YATE_SCHPO Hypothetical protein C1D4.14 in...   370   e-100
gi|4691407|emb|CAA91079.2| SPAC22F3.14c [Schizosaccharomyces pombe]   370   e-100
gi|10435650|dbj|BAB14630.1| unnamed protein product [Homo sapiens]    367   1e-99
gi|49089264|ref|XP_406363.1| hypothetical protein AN2226.2 [Aspe...   313   3e-83
gi|50260034|gb|EAL22697.1| hypothetical protein CNBB1460 [Crypto...   264   2e-68
gi|50545197|ref|XP_500136.1| hypothetical protein [Yarrowia lipo...   249   3e-64
gi|46122559|ref|XP_385833.1| hypothetical protein FG05657.1 [Gib...   249   4e-64
gi|38110038|gb|EAA55817.1| hypothetical protein MG01468.4 [Magna...   249   5e-64
gi|27311827|gb|AAO00879.1| F5A9.22 [Arabidopsis thaliana]             247   2e-63
gi|32413617|ref|XP_327288.1| hypothetical protein [Neurospora cr...   246   3e-63
gi|39795453|gb|AAH63692.1| THOC2 protein [Homo sapiens]               234   1e-59
gi|38086122|ref|XP_284697.2| similar to Tho2 [Mus musculus]           204   1e-50
gi|15292305|gb|AAK93421.1| LD46453p [Drosophila melanogaster]         198   8e-49
gi|50418917|ref|XP_457979.1| unnamed protein product [Debaryomyc...   193   3e-47
gi|46431457|gb|EAK91017.1| hypothetical protein CaO19.4123 [Cand...   185   9e-45
gi|6324190|ref|NP_014260.1| Required for LacZ RNA expression fro...   162   5e-38
gi|50303133|ref|XP_451504.1| unnamed protein product [Kluyveromy...   149   4e-34
gi|50291037|ref|XP_447951.1| unnamed protein product [Candida gl...   138   1e-30
gi|45198576|ref|NP_985605.1| AFR058Cp [Eremothecium gossypii] >g...   135   1e-29
gi|38087092|ref|XP_359343.1| similar to SI:bZ1O18.2 (novel prote...   102   1e-19
gi|23487926|gb|EAA21180.1| hypothetical protein [Plasmodium yoel...    89   9e-16
gi|23509170|ref|NP_701838.1| hypothetical protein [Plasmodium fa...    77   5e-12
gi|462013|sp|P35016|ENPL_CATRO Endoplasmin homolog precursor (GR...    45   0.020
gi|23508231|ref|NP_700900.1| hypothetical protein [Plasmodium fa...    44   0.034
gi|39585444|emb|CAE70527.1| Hypothetical protein CBG17156 [Caeno...    42   0.17
gi|46433585|gb|EAK93020.1| hypothetical protein CaO19.14145 [Can...    40   0.64
gi|23613424|ref|NP_703268.1| hypothetical protein [Plasmodium fa...    39   0.84
gi|23509866|ref|NP_702533.1| hypothetical protein [Plasmodium fa...    39   1.1
gi|42566924|ref|NP_193558.3| starch synthase-related protein [Ar...    39   1.4
gi|50741956|ref|XP_419638.1| PREDICTED: similar to hypothetical ...    39   1.4
gi|7488349|pir||T04926 starch synthase homolog T9A21.90 - Arabid...    39   1.4
gi|46433616|gb|EAK93050.1| hypothetical protein CaO19.6855 [Cand...    38   1.9
gi|10956594|ref|NP_052564.1| transposase TnpA [Corynebacterium g...    38   2.4
gi|9294477|dbj|BAB02696.1| RING finger protein-like [Arabidopsis...    37   3.2
gi|12711674|ref|NP_075386.1| UPF3 regulator of nonsense transcri...    37   4.2
gi|27802451|gb|AAO21372.1| maturase [Ocimum basilicum]                 37   4.2
gi|28436870|gb|AAH47049.1| Upf3b protein [Mus musculus]                37   5.5
gi|25056787|ref|XP_110787.2| UPF3 regulator of nonsense transcri...    37   5.5
gi|25144991|ref|NP_741394.1| casein kinase family member (4G79) ...    37   5.5
gi|32405254|ref|XP_323240.1| hypothetical protein ( related to B...    36   7.1
gi|46442512|gb|EAL01801.1| hypothetical protein CaO19.4329 [Cand...    36   7.1
gi|39581964|emb|CAE73826.1| Hypothetical protein CBG21388 [Caeno...    36   7.1
gi|46229368|gb|EAK90186.1| hypothetical protein containing a sig...    36   7.1
gi|23024989|ref|ZP_00064173.1| COG2207: AraC-type DNA-binding do...    36   7.1
gi|26341966|dbj|BAC34645.1| unnamed protein product [Mus musculus]     36   7.1
gi|19387031|gb|AAL87095.1| HSP70 [Actinomadura spadix]                 36   7.1
gi|37361880|gb|AAQ91053.1| LRRGT00097 [Rattus norvegicus]              36   9.3
gi|18376078|emb|CAD21105.1| hypothetical protein [Neurospora cra...    36   9.3
gi|24580684|ref|NP_608540.1| CG2839-PA [Drosophila melanogaster]...    36   9.3
gi|677198|gb|AAB00143.1| putative                                      36   9.3
gi|15236799|ref|NP_193556.1| purine permease family protein [Ara...    36   9.3
gi|1903280|emb|CAA98620.1| USO1 [Saccharomyces cerevisiae]             36   9.3
gi|6320145|ref|NP_010225.1| involved intracellular protein trans...    36   9.3
gi|137175|sp|P25386|USO1_YEAST Intracellular protein transport p...    36   9.3


>gi|17552208|ref|NP_498392.1| tho2 (164.4 kD) (3H463) [Caenorhabditis
            elegans]
 gi|14573810|gb|AAB47593.3| Hypothetical protein C16A3.8
            [Caenorhabditis elegans]
          Length = 1437

 Score = 2472 bits (6408), Expect = 0.0
 Identities = 1282/1437 (89%), Positives = 1282/1437 (89%)
 Frame = +1

Query: 1    MNDFETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNAS 180
            MNDFETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNAS
Sbjct: 1    MNDFETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNAS 60

Query: 181  TSKENFESFVNLLTNTIIPEEILRLELDCFKKDDHSKALIRLKTKVYFKQAKFNLFREES 360
            TSKENFESFVNLLTNTIIPEEILRLELDCFKKDDHSKALIRLKTKVYFKQAKFNLFREES
Sbjct: 61   TSKENFESFVNLLTNTIIPEEILRLELDCFKKDDHSKALIRLKTKVYFKQAKFNLFREES 120

Query: 361  EGYSKLVTELMXXXXXXXXXXXXXKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQK 540
            EGYSKLVTELM             KILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQK
Sbjct: 121  EGYSKLVTELMEAAESSANENEHAKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQK 180

Query: 541  LLFIALLKEIDVVRDYLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILG 720
            LLFIALLKEIDVVRDYLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILG
Sbjct: 181  LLFIALLKEIDVVRDYLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILG 240

Query: 721  YMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATTQTISFT 900
            YMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATTQTISFT
Sbjct: 241  YMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATTQTISFT 300

Query: 901  TVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQAS 1080
            TVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQAS
Sbjct: 301  TVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQAS 360

Query: 1081 PRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLSS 1260
            PRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLSS
Sbjct: 361  PRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLSS 420

Query: 1261 VLAYLGPRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFVEVVSECLLPSLTLS 1440
            VLAYLGPRIAFRASTNIKIVRLLTAYYR             NQNFVEVVSECLLPSLTLS
Sbjct: 421  VLAYLGPRIAFRASTNIKIVRLLTAYYRKVDKDLLPKDDKLNQNFVEVVSECLLPSLTLS 480

Query: 1441 ETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTKYVLKRLSKE 1620
            ETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTKYVLKRLSKE
Sbjct: 481  ETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTKYVLKRLSKE 540

Query: 1621 TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ 1800
            TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ
Sbjct: 541  TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ 600

Query: 1801 LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL 1980
            LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL
Sbjct: 601  LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL 660

Query: 1981 REIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLA 2160
            REIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLA
Sbjct: 661  REIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLA 720

Query: 2161 VGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPT 2340
            VGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPT
Sbjct: 721  VGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPT 780

Query: 2341 VRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFT 2520
            VRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFT
Sbjct: 781  VRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFT 840

Query: 2521 SALESQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSR 2700
            SALESQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSR
Sbjct: 841  SALESQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSR 900

Query: 2701 EDSHGKAKKTDKQLESKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQC 2880
            EDSHGKAKKTDKQLESKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQC
Sbjct: 901  EDSHGKAKKTDKQLESKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQC 960

Query: 2881 LLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLAC 3060
            LLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLAC
Sbjct: 961  LLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLAC 1020

Query: 3061 FFEILLCTVQRWHSEKEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFT 3240
            FFEILLCTVQRWHSEKEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFT
Sbjct: 1021 FFEILLCTVQRWHSEKEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFT 1080

Query: 3241 KDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVG 3420
            KDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVG
Sbjct: 1081 KDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVG 1140

Query: 3421 KLKMRTVKIYAQNSDYAPVPNKKVSXXXXXXXXXXXXXXXXXXXXXXPVDKKIKVDSKKN 3600
            KLKMRTVKIYAQNSDYAPVPNKKVS                      PVDKKIKVDSKKN
Sbjct: 1141 KLKMRTVKIYAQNSDYAPVPNKKVSVGAEKPKKKEKVVDEKDKADGEPVDKKIKVDSKKN 1200

Query: 3601 GTTSSEKVVKDDEVHQNGSETEKKATVDNKERKKRPXXXXXXXXXXXXXPTTEDGEVKTP 3780
            GTTSSEKVVKDDEVHQNGSETEKKATVDNKERKKRP             PTTEDGEVKTP
Sbjct: 1201 GTTSSEKVVKDDEVHQNGSETEKKATVDNKERKKRPGKSSHGSKESKKEPTTEDGEVKTP 1260

Query: 3781 SPPPAKKTRIVDRLKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGXXXXXXXX 3960
            SPPPAKKTRIVDRLKR                                  TG
Sbjct: 1261 SPPPAKKTRIVDRLKRSDEPSKKDEKESPKDTESEKGEGKKRRERSKDKETGKEKRLEKD 1320

Query: 3961 XXXXXXXXXXXXXXXXXQKEQKILKDQKQKSKPSDEKLEVAGPALXXXXXXXXXXXGSRK 4140
                             QKEQKILKDQKQKSKPSDEKLEVAGPAL           GSRK
Sbjct: 1321 NKEREKDKERKRENGENQKEQKILKDQKQKSKPSDEKLEVAGPALPDPVPKKDDKKGSRK 1380

Query: 4141 AIEFDLXXXXXXXXXXXXXXXXXXXXXXXXLPKASRIAEPARDAGKSGRDRGHRTFR 4311
            AIEFDL                        LPKASRIAEPARDAGKSGRDRGHRTFR
Sbjct: 1381 AIEFDLEEPSKSTSSSRKDRKDDRKEKKEELPKASRIAEPARDAGKSGRDRGHRTFR 1437


>gi|25395798|pir||G88480 protein C16A3.7 [imported] - Caenorhabditis
            elegans
          Length = 1242

 Score = 2032 bits (5265), Expect = 0.0
 Identities = 1063/1242 (85%), Positives = 1064/1242 (85%), Gaps = 36/1242 (2%)
 Frame = +1

Query: 694  MIDMMKILGYMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGN 873
            MIDMMKILGYMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGN
Sbjct: 1    MIDMMKILGYMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGN 60

Query: 874  ATTQTISFTTVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRL 1053
            ATTQTISFTTVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRL
Sbjct: 61   ATTQTISFTTVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRL 120

Query: 1054 PEYYAVQASPRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIES 1233
            PEYYAVQASPRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIES
Sbjct: 121  PEYYAVQASPRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIES 180

Query: 1234 WEDLGKLSSVLAYLGPRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFVEVVSE 1413
            WEDLGKLSSVLAYLGPRIAFRASTNIKIVRLLTAYYR             NQNFVEVVSE
Sbjct: 181  WEDLGKLSSVLAYLGPRIAFRASTNIKIVRLLTAYYRKVDKDLLPKDDKLNQNFVEVVSE 240

Query: 1414 CLLPSLTLSETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTK 1593
            CLLPSLTLSETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTK
Sbjct: 241  CLLPSLTLSETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTK 300

Query: 1594 YVLKRLSKETVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFD 1773
            YVLKRLSKETVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFD
Sbjct: 301  YVLKRLSKETVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFD 360

Query: 1774 VLTY------------------------------------CIISQLADPSKQALKSTDAT 1845
            VLT+                                    CIISQLADPSKQALKSTDAT
Sbjct: 361  VLTFSYVKKFSFFSFTCKQVKLFQIYFKYFSFEGFPFIPDCIISQLADPSKQALKSTDAT 420

Query: 1846 ISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISG 2025
            ISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISG
Sbjct: 421  ISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISG 480

Query: 2026 ATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIV 2205
            ATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIV
Sbjct: 481  ATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIV 540

Query: 2206 YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEAT 2385
            YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEAT
Sbjct: 541  YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEAT 600

Query: 2386 MCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLMDELK 2565
            MCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLMDELK
Sbjct: 601  MCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLMDELK 660

Query: 2566 ASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSREDSHGKAKKTDKQLE 2745
            ASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSREDSHGKAKKTDKQLE
Sbjct: 661  ASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSREDSHGKAKKTDKQLE 720

Query: 2746 SKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQCLLPRAIFSELDAVFC 2925
            SKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQCLLPRAIFSELDAVFC
Sbjct: 721  SKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEALIQQCLLPRAIFSELDAVFC 780

Query: 2926 GQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFFEILLCTVQRWHSE 3105
            GQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFFEILLCTVQRWHSE
Sbjct: 781  GQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFFEILLCTVQRWHSE 840

Query: 3106 KEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIM 3285
            KEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIM
Sbjct: 841  KEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIM 900

Query: 3286 MTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQNSD 3465
            MTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQNSD
Sbjct: 901  MTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQNSD 960

Query: 3466 YAPVPNKKVSXXXXXXXXXXXXXXXXXXXXXXPVDKKIKVDSKKNGTTSSEKVVKDDEVH 3645
            YAPVPNKKVS                      PVDKKIKVDSKKNGTTSSEKVVKDDEVH
Sbjct: 961  YAPVPNKKVSVGAEKPKKKEKVVDEKDKADGEPVDKKIKVDSKKNGTTSSEKVVKDDEVH 1020

Query: 3646 QNGSETEKKATVDNKERKKRPXXXXXXXXXXXXXPTTEDGEVKTPSPPPAKKTRIVDRLK 3825
            QNGSETEKKATVDNKERKKRP             PTTEDGEVKTPSPPPAKKTRIVDRLK
Sbjct: 1021 QNGSETEKKATVDNKERKKRPGKSSHGSKESKKEPTTEDGEVKTPSPPPAKKTRIVDRLK 1080

Query: 3826 RXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTGXXXXXXXXXXXXXXXXXXXXXXX 4005
            R                                  TG
Sbjct: 1081 RSDEPSKKDEKESPKDTESEKGEGKKRRERSKDKETGKEKRLEKDNKEREKDKERKRENG 1140

Query: 4006 XXQKEQKILKDQKQKSKPSDEKLEVAGPALXXXXXXXXXXXGSRKAIEFDLXXXXXXXXX 4185
              QKEQKILKDQKQKSKPSDEKLEVAGPAL           GSRKAIEFDL
Sbjct: 1141 ENQKEQKILKDQKQKSKPSDEKLEVAGPALPDPVPKKDDKKGSRKAIEFDLEEPSKSTSS 1200

Query: 4186 XXXXXXXXXXXXXXXLPKASRIAEPARDAGKSGRDRGHRTFR 4311
                           LPKASRIAEPARDAGKSGRDRGHRTFR
Sbjct: 1201 SRKDRKDDRKEKKEELPKASRIAEPARDAGKSGRDRGHRTFR 1242


>gi|39584988|emb|CAE64412.1| Hypothetical protein CBG09105
            [Caenorhabditis briggsae]
          Length = 1427

 Score = 1985 bits (5142), Expect = 0.0
 Identities = 1038/1466 (70%), Positives = 1170/1466 (79%), Gaps = 29/1466 (1%)
 Frame = +1

Query: 1    MNDFETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNAS 180
            M  FE LTQLCLDIVHMKIT  + +ERIL +K +R+A+SS+L+DVLVLTEPESEFA+NAS
Sbjct: 1    MEMFEVLTQLCLDIVHMKITAAEGFERILEKKNEREALSSDLVDVLVLTEPESEFAENAS 60

Query: 181  TSKENFESFVNLLTNTIIPEEILRLELDCFKKDDHSKALIRLKTKVYFKQAKFNLFREES 360
            TSK NFESFV+LLTNTIIPEEILRLELDC K+D+H+K LIRLKTK+YFKQAKFNLFREES
Sbjct: 61   TSKANFESFVHLLTNTIIPEEILRLELDCCKRDEHNKGLIRLKTKLYFKQAKFNLFREES 120

Query: 361  EGYSKLVTELMXXXXXXXXXXXXXKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQK 540
            EGYSKL+TELM             K++KHRVLSLIGQFNLDPNRVTD+ILEVFE FP+QK
Sbjct: 121  EGYSKLITELMESSENCSAHDDFAKVIKHRVLSLIGQFNLDPNRVTDIILEVFEIFPKQK 180

Query: 541  LLFIALLKEIDVVRDYLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILG 720
            + FI+LLKEIDVV +YLCA+LGFK+TFYQS+KKK TPYSLYVLTA LIQHEMID+MKIL
Sbjct: 181  MFFISLLKEIDVVPEYLCAILGFKYTFYQSEKKK-TPYSLYVLTAYLIQHEMIDLMKILA 239

Query: 721  YMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATTQTISFT 900
            YMIPKAEAIKE H++RM NAQERASKAETISTAS+P+ DS    E G+GG   T  IS T
Sbjct: 240  YMIPKAEAIKESHKARMVNAQERASKAETISTASIPMTDS----EIGMGGPVVT--ISIT 293

Query: 901  TVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQAS 1080
            TVIQLQEDED KL+EGFNEE VL+SNQKLGL CALLE+GNWKQAQ LIDRLPEYYAVQAS
Sbjct: 294  TVIQLQEDEDAKLAEGFNEESVLASNQKLGLACALLENGNWKQAQHLIDRLPEYYAVQAS 353

Query: 1081 PRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLSS 1260
            PR+CRALCKIIE+SI+ FY+K+CSLNLFG+L KS KPVLDDMGNGL+PI+SW+DLG+L +
Sbjct: 354  PRVCRALCKIIERSIDAFYRKSCSLNLFGELTKSKKPVLDDMGNGLKPIDSWDDLGQLVT 413

Query: 1261 VLAYLGPRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFVEVVSECLLPSLTLS 1440
            +LAYLGPR+A+RA+TNIKI+RLLTAYY+             N+ FVE+VSECLLPSLTLS
Sbjct: 414  ILAYLGPRLAYRATTNIKILRLLTAYYQKVEKGELQKDEKLNELFVELVSECLLPSLTLS 473

Query: 1441 ETNVALSEEIWQLLELFPYSWRYWMYSKWNLETSRHPEMHIMKGKIHGRTKYVLKRLSKE 1620
            +TNVALSEE+WQLL+LFPYSWRYWMYSKWN ET RHPEM IM+GK+HGRTKYVLKRLSKE
Sbjct: 474  DTNVALSEELWQLLQLFPYSWRYWMYSKWNHETMRHPEMSIMRGKVHGRTKYVLKRLSKE 533

Query: 1621 TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ 1800
            TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ
Sbjct: 534  TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ 593

Query: 1801 LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL 1980
            LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL
Sbjct: 594  LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL 653

Query: 1981 REIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLA 2160
            REIIQNMSWIESISGATKEQIEALGGGDLL+QEA GYSTATKNRKAAQRLRDALLKGDLA
Sbjct: 654  REIIQNMSWIESISGATKEQIEALGGGDLLRQEAGGYSTATKNRKAAQRLRDALLKGDLA 713

Query: 2161 VGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPT 2340
            VGL IS+AQQKEHI+YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVY++N+DF+KRVP+
Sbjct: 714  VGLCISIAQQKEHIMYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYMRNEDFAKRVPS 773

Query: 2341 VRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVE----DGQKTRLDTQQKT 2508
            VREL++DYSLGMEATMCLARP FFSRI D+YD+AKK+SKAA +      +KTRLD+QQKT
Sbjct: 774  VRELIADYSLGMEATMCLARPTFFSRILDNYDSAKKVSKAAADAEAGGDKKTRLDSQQKT 833

Query: 2509 EMFTSALESQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALK 2688
            E+FT+ALE+Q+E LM++LK +   MEE++PV+FFAVFWMLTMYDIEVPT+AY+RTL+A+K
Sbjct: 834  EIFTNALEAQIEALMNDLKEANSAMEESVPVRFFAVFWMLTMYDIEVPTSAYDRTLEAMK 893

Query: 2689 KQSREDSHGKAKKTDKQLESKLREEQKRQIEHVERCKVWLLNKKDSLIDEQFHNSVLEAL 2868
            KQSR+DSHGK KKTDKQLESKLREEQKRQ EHVERCK WLL++KDSLIDE+FHNSVLE L
Sbjct: 894  KQSRDDSHGKPKKTDKQLESKLREEQKRQTEHVERCKAWLLSRKDSLIDEKFHNSVLEVL 953

Query: 2869 IQQCLLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEAN 3048
            IQQCLLPRAIFSELDAVFCGQFF MLHEMRTPFFPS++IIDRLFEN IPLIAGLTE+EAN
Sbjct: 954  IQQCLLPRAIFSELDAVFCGQFFKMLHEMRTPFFPSIVIIDRLFENTIPLIAGLTEDEAN 1013

Query: 3049 SLACFFEILLCTVQRWHSEKEVFEKECAGFPGMITKQAIEYQTFRKLCYRWQIRFTAMFK 3228
            +LACFFEILL   QRWHSEKE+FEKECAGFPGMITK AIEYQTFRKLCYRWQ RFT MFK
Sbjct: 1014 ALACFFEILLGLTQRWHSEKEIFEKECAGFPGMITKNAIEYQTFRKLCYRWQTRFTLMFK 1073

Query: 3229 TVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAA 3408
            +V +K+D++YVLIRNSLIMMTKLT+GFP+I+  VATME   TKLK+REKGKRDDLSLKAA
Sbjct: 1074 SVLSKEDSNYVLIRNSLIMMTKLTTGFPLIAANVATMEATATKLKEREKGKRDDLSLKAA 1133

Query: 3409 SYVGKLKMRTVKIYAQNSDYAPVPNKKVSXXXXXXXXXXXXXXXXXXXXXXPVDKKIKVD 3588
            SY+GKLKMR VKIYAQNSD+A VPN+K S                      P DKK+KVD
Sbjct: 1134 SYIGKLKMRNVKIYAQNSDFANVPNRKAS------TVEKKEKKKSDKEEGEPADKKLKVD 1187

Query: 3589 SKKNGTTSSEKV-----VKDDEVHQNGS---ETEKKATV----DNKERKKRPXXXXXXXX 3732
            +KKNGT+S + +      K++E  QNG+   + EKK T     +NK+RKKRP
Sbjct: 1188 AKKNGTSSEKNLEKKEEKKEEEEKQNGAGSEKVEKKTTTTTPDENKDRKKRPGKSSDSTS 1247

Query: 3733 XXXXXPTTEDGEVKTPSPPPAKKTRIVDRLKRXXXXXXXXXXXXXXXXXXXXXXXXXXXX 3912
                     D E KT SPPPAKKTRI DRLK
Sbjct: 1248 SKKA-----DEETKTTSPPPAKKTRITDRLKH---------------------PEDEKEV 1281

Query: 3913 XXXXXXTGXXXXXXXXXXXXXXXXXXXXXXXXXQKEQKILKDQKQK-----SKPSDEKLE 4077
                   G                          ++++   D K+K      K  +++ E
Sbjct: 1282 KDTESEKGEGSKKKREKSRERKDKEKRSSEKDKDRKKENGGDGKEKKEKEHQKKDEKRAE 1341

Query: 4078 VAGPAL--XXXXXXXXXXXGSRKAIEFDLX------XXXXXXXXXXXXXXXXXXXXXXXL 4233
            VAGPAL              SRK IEFDL                              L
Sbjct: 1342 VAGPALPEPKKDEKKDDKKSSRKTIEFDLSDSPKTPAATSSSSRKDRERKEEKKEKREDL 1401

Query: 4234 PKASRIAEPARDAGKSGRDRGHRTFR 4311
            PK+SRIAEP + AG+   DRGHR+ R
Sbjct: 1402 PKSSRIAEPVK-AGRDRGDRGHRSHR 1426


>gi|49619103|gb|AAT68136.1| Tho2 [Danio rerio]
          Length = 1504

 Score =  677 bits (1746), Expect = 0.0
 Identities = 410/1156 (35%), Positives = 643/1156 (55%), Gaps = 37/1156 (3%)
 Frame = +1

Query: 103  RDAISSELIDVLVLTEPESEFADNASTSKENFESFVNLLTNTII--PEEILRLELD---- 264
            RD + S L DVL + + E+   +     K   + F  L+   +I  P+ +L+  LD
Sbjct: 74   RDDMPSILADVLCILDIETGCLEE----KHKRDLFTQLVGACLICIPDGVLKERLDPETL 129

Query: 265  -----CFKKDDHSKALIRLKTKVYFKQAKFNLFREESEGYSKLVTELMXXXXXXXXXXXX 429
                   +    ++ ++++KTK+++KQ KFNL REE+EGY+KL+TEL
Sbjct: 130  ESLGLIKQAQQFNQKIVKIKTKLFYKQQKFNLLREENEGYAKLITEL----GQDLTGNLT 185

Query: 430  XKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEIDVVRDYLCALLGF 609
              I+   + SLIG FNLDPNRV D+ILEV+E    Q   FI L+K        LC +LGF
Sbjct: 186  SHIVLENIKSLIGCFNLDPNRVLDIILEVYECRSDQDEFFIPLIKSYMCEHQTLCHMLGF 245

Query: 610  KFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAIKEGHRSRMQNAQER 789
            KF F+Q +   +TP SLY + A+L+QH++I +  +  +++P   +I E H+  +  A++
Sbjct: 246  KFKFHQ-EPNGETPSSLYHIAAALLQHDLIALEDLYVHLLPLDSSIVEEHKRDILEAKQI 304

Query: 790  ASKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDEDIKLSEGFNEEYVL 969
            A K   +   S    D                        + ++D++    E  NE+
Sbjct: 305  ARKLTMVVLPSEKTEDK-----------------------EKEKDKE----EEKNEKP-- 335

Query: 970  SSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCKIIEKSINDFYKK-N 1146
              NQKLGL  ALL   +W+ +Q ++D+LP +YA  +   +  ALC+++   I+  Y++
Sbjct: 336  PDNQKLGLLEALLRISDWQHSQSIMDQLPAFYAT-SHKAIAVALCQLLHLIIDPLYRRAG 394

Query: 1147 CSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGK-LSSVLAYLGPRIAFRASTNIKIVR 1323
                  G LI   +       +   P E+++DL + + ++L YLGP ++       K+VR
Sbjct: 395  VPKGAKGSLITPLQNK-----HAPHPAENFDDLSRDVFTMLCYLGPHLSHDPILFAKMVR 449

Query: 1324 LLTAYYRXXXXXXXXXXXXXNQNFVEVVSECLLPSLTLSETNVALSEEIWQLLELFPYSW 1503
            L  ++ +               +F+ +  + LLPSL+L E N  +SEE+W   + FPY
Sbjct: 450  LGKSFMKEDSLLG---------SFLSIADQVLLPSLSLMECNACMSEELWGFFKFFPYQH 500

Query: 1504 RYWMYSKWNLET-SRHPEMHIMKGKIHGRTKYVLKRLSKETVKMMGRQLGKLCHIHPSTV 1680
            RY +Y +W  ET S HP +  +K +   R+KY++KRL+KE VK  GRQ+GKL H +P+ +
Sbjct: 501  RYRLYGQWKNETYSNHPLLVKIKAQTVDRSKYIMKRLTKENVKPSGRQIGKLSHSNPTIL 560

Query: 1681 LSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQLADPSKQALKSTDATISPWL 1860
              Y+LSQ+Q +DN I PVVDSL+YLTSL +DVL YCII  LA+P K+ +K  D TIS WL
Sbjct: 561  FDYILSQIQWYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKEKMKHDDTTISSWL 620

Query: 1861 QALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISGATKEQ 2040
            Q+L +L G+++R+YP+EL G+L YV NQLK  KS+D+L+L+E++Q M+ IE     T EQ
Sbjct: 621  QSLASLCGAVFRKYPIELAGLLQYVTNQLKAGKSFDLLILKEVVQKMAGIEITDEMTVEQ 680

Query: 2041 IEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIVYNESS 2220
            +EA+ GG+ LK E   +      +K++QRL+DALL  +LA+ L + +AQQ+  +V++E
Sbjct: 681  LEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHELALPLCLLMAQQRNGVVFSEGG 740

Query: 2221 TLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEATMCLAR 2400
               LKLVGK+ DQC DT  Q   FL+  L  +D+ KRVP+V  L +      +A   L+R
Sbjct: 741  EKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSVDVLCNQLHTPHDAAFFLSR 800

Query: 2401 PIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLMDELKASE-P 2577
            P++  +I   YD  KK  K   +         QQK   + +A E  +  + + + +   P
Sbjct: 801  PMYAHQILSKYDELKKAEKGNRQ---------QQKVHKYITACEQVMAPVHEAVVSLHLP 851

Query: 2578 GMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSRE-----DSHGKAKKTDKQ- 2739
             + +++  +F+A FW LTMYD+ VP  AY+R ++ LK Q +      +     KK +K+
Sbjct: 852  KVWDDLRPQFYATFWSLTMYDLAVPHNAYDREVNKLKMQIKSIDDNTEMPPNKKKKEKER 911

Query: 2740 ---LESKLREEQKRQIEHVERCKVWLLNKKDS-LIDEQFHNSVLEALIQQCLLPRAIFSE 2907
               L+ KL+EE+K+Q+EHV+R    L  +KD+ L+ +   N  +   +Q C+ PR +FS
Sbjct: 912  CTALQDKLQEEEKKQLEHVQRVLHRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCVFSA 971

Query: 2908 LDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFFEILLCTV 3087
            +DAV+C +F  ++H+ +TP F ++L  DR+F +II  +A  TENE+     F   +L TV
Sbjct: 972  IDAVYCARFVELVHQQKTPNFCTLLCYDRVFSDIIYTVASCTENESRRYGRFLCCMLETV 1031

Query: 3088 QRWHSEKEVFEKECAGFPGMIT------------KQAIEYQTFRKLCYRWQIRFTAMFKT 3231
             RWHS++ ++EKEC  +PG +T               ++Y+ FR + ++W  + T    +
Sbjct: 1032 TRWHSDRAIYEKECGNYPGFLTIFRASGFDGGNKADQLDYENFRHVVHKWHYKLTK--AS 1089

Query: 3232 VFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAAS 3411
            V   +  +Y  IRN LI++TK+   +P + +    +E  V K+   EK KR DL   A
Sbjct: 1090 VHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALECRVHKICQEEKEKRPDLYALAMG 1149

Query: 3412 YVGKLKMRTVKIYAQN 3459
            Y G+LK R V +  +N
Sbjct: 1150 YSGQLKGRKVHMVPEN 1165


>gi|50745998|ref|XP_420332.1| PREDICTED: similar to THO complex
            subunit 2 (Tho2) [Gallus gallus]
          Length = 1634

 Score =  672 bits (1734), Expect = 0.0
 Identities = 408/1164 (35%), Positives = 642/1164 (55%), Gaps = 45/1164 (3%)
 Frame = +1

Query: 103  RDAISSELIDVLVLTEPESEFADNASTSKENFESFV----NLLTNTIIPEEILRLELDCF 270
            R+ + S L D   + + E+   +   T ++ F   V     L+++T++ E +    L+
Sbjct: 74   REDMPSILADAFCILDIETSCLEE-KTKRDCFTQLVLSCLYLVSDTVLKERLDPETLESL 132

Query: 271  ----KKDDHSKALIRLKTKVYFKQAKFNLFREESEGYSKLVTELMXXXXXXXXXXXXXKI 438
                +    ++  +++KTK+++KQ KFNL REE+EGY+KL+ EL               +
Sbjct: 133  GLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAEL----GQDLSGNITSDL 188

Query: 439  LKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEIDVVRD--YLCALLGFK 612
            +   + SLIG FNLDPNRV D+ILEV+E  P     F+ L++    + +   LC +LGFK
Sbjct: 189  ILENIKSLIGCFNLDPNRVLDIILEVYECRPEYDDFFVPLIESYMYMCEPQTLCHILGFK 248

Query: 613  FTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAIKEGHRSRMQNAQERA 792
            F FYQ D   +TP SLY + A L+QH +ID+  +  +++P   AI E H+  +  A++
Sbjct: 249  FKFYQ-DPSGETPSSLYRVAAVLLQHNLIDLEDLYVHLLPGDNAIIEEHKREIVEAKQIV 307

Query: 793  SKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDEDIKLSEGFNEEYVLS 972
             K       +M ++ S   +E                    +E E  K  E   +
Sbjct: 308  RKL------TMVVLSSEKTEE--------------------KEKEKEKEEEKTEKP---P 338

Query: 973  SNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCKIIEKSINDFYKKNCS 1152
             NQKLGL  ALL+ G+W+ AQ ++D++P +YA    P +  ALC+++  +I   Y++
Sbjct: 339  DNQKLGLLEALLKIGDWQHAQSIMDQMPPFYATSHKP-IAIALCQLVHVTIEPLYRR--- 394

Query: 1153 LNLFGDLIKSTKPVLDDMGNGLRP--IESWEDLGK-LSSVLAYLGPRIAFRASTNIKIVR 1323
                G    +    +  + N   P   +S+EDL K + ++L YLGP ++       K+VR
Sbjct: 395  ---VGVPKGAKGSPISPLPNKRAPKQADSFEDLRKEVFNMLCYLGPHLSHDPILFAKVVR 451

Query: 1324 LLTAYYRXXXXXXXXXXXXXNQNFV-----EVVSECLLPSLTLSETNVALSEEIWQLLEL 1488
            L  A+ +                 +      +  + LLPSL+L + N  +SEE+W + +
Sbjct: 452  LGKAFMKEFQSDGSKQEDKEKMEILFSCVLSITDQVLLPSLSLMDCNACMSEELWGMFKT 511

Query: 1489 FPYSWRYWMYSKWNLET-SRHPEMHIMKGKIHGRTKYVLKRLSKETVKMMGRQLGKLCHI 1665
            FPY +RY +Y +W  ET + HP +  +K +   R KY++KRL+KE VK  GRQ+GKL H
Sbjct: 512  FPYQYRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHA 571

Query: 1666 HPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQLADPSKQALKSTDAT 1845
            +P+ +  Y+LSQ+Q +DN I PVVDSL+YLTSL +DVL YCII  LA+P K+ +K  D T
Sbjct: 572  NPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTT 631

Query: 1846 ISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISG 2025
            IS WLQ+L +  G+++R+YP+EL G+L YV NQLK  KS+D+L+L+E++Q M+ IE
Sbjct: 632  ISSWLQSLASFCGAVFRKYPIELAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEE 691

Query: 2026 ATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIV 2205
             T EQ+EA+ GG+ LK E   +      +K++QRL+DALL  DLA+ L + +AQQ+  ++
Sbjct: 692  MTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVI 751

Query: 2206 YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEAT 2385
            + E     LKLVGK+ DQC DT  Q   FL+  L  +D+ KRVP++  L +++    +A
Sbjct: 752  FQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAA 811

Query: 2386 MCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLMDE-L 2562
              L+RP++  +IS  YD  KK      E G K     Q K   + +A E  +  + +  +
Sbjct: 812  FFLSRPMYAHQISSKYDELKK-----AEKGNK----QQHKVHKYITACELVMAPVHEAVI 862

Query: 2563 KASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSR-----EDSHGKAKK 2727
                P + ++I  +F+A FW LTMYD+ VP ++Y+R ++ LK Q +     ++     KK
Sbjct: 863  SLHPPKVWDDISPQFYATFWSLTMYDLAVPHSSYDREVNKLKVQMKAIDDNQEMPPNKKK 922

Query: 2728 TDKQ----LESKLREEQKRQIEHVERCKVWLLNKKDS-LIDEQFHNSVLEALIQQCLLPR 2892
             +K+    L+ KL EE+K+Q+EHV+R    L  +KD+ L+ +   N  +   +Q C+ PR
Sbjct: 923  KEKERCTALQDKLLEEEKKQLEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIFPR 982

Query: 2893 AIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFFEI 3072
             IFS +DAV+C  F  ++H+ +TP F ++L  DR+F +II  +A  TENEA+    F
Sbjct: 983  CIFSAIDAVYCAHFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCC 1042

Query: 3073 LLCTVQRWHSEKEVFE---KECAGFPGMIT------------KQAIEYQTFRKLCYRWQI 3207
            +L TV RWHS++ ++E   KEC  +PG +T               ++Y+ FR + ++W
Sbjct: 1043 MLETVTRWHSDRVIYEKVCKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHY 1102

Query: 3208 RFTAMFKTVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRD 3387
            + T    +V   +  +Y  IRN LI++TK+   +P + +    +E  V K+   EK KR
Sbjct: 1103 KLTK--ASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKRP 1160

Query: 3388 DLSLKAASYVGKLKMRTVKIYAQN 3459
            DL   A  Y G+LK R   +  +N
Sbjct: 1161 DLYALAMGYSGQLKSRKPFMIPEN 1184


>gi|47222567|emb|CAG02932.1| unnamed protein product [Tetraodon
            nigroviridis]
          Length = 1544

 Score =  671 bits (1731), Expect = 0.0
 Identities = 417/1165 (35%), Positives = 644/1165 (54%), Gaps = 46/1165 (3%)
 Frame = +1

Query: 103  RDAISSELIDVLVLTEPESEFADNASTSKENFESFVNLLTNTII--PEEILRLELDC--- 267
            RD + S L DV  + + E+    +A   K   + +  L+   ++  PE IL+  LD
Sbjct: 74   RDDMPSILADVFCILDIET----SALEEKHRRDHYTQLVGACLVCVPEAILKERLDPETL 129

Query: 268  ----FKKDDH--SKALIRLKTKVYFKQAKFNLFREESEGYSKLVTELMXXXXXXXXXXXX 429
                  K  H  ++ ++++KTK+++KQ KFNL REE+EGY+KL+TEL
Sbjct: 130  ESLGLIKQAHQFNQKIVKIKTKLFYKQQKFNLLREENEGYAKLITELGQDLSGNITSHLV 189

Query: 430  XKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEIDVVRDYLCALLGF 609
             + +K    SLIG FNLDPNRV D+ILEV+E+   Q   F++L+K        LC +LGF
Sbjct: 190  LESIK----SLIGCFNLDPNRVLDIILEVYESRADQDEFFLSLIKSYMCEPLTLCHILGF 245

Query: 610  KFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAIKEGHRSRMQNAQER 789
            KF FYQ +  ++TP SLY + A+L+ H +I +  I  +++P    I E H+  +  A++
Sbjct: 246  KFKFYQ-EPNEETPKSLYHVAAALLHHNLIALEDIYVHLMPPDVTIVEEHKRGISEAKQF 304

Query: 790  ASKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDEDIKLSEGFNEEYVL 969
            A K        MP++ +   D+N                    ED+D    +  N++  L
Sbjct: 305  ARKLV------MPVLPT---DKN--------------------EDKDKDKEDDKNDK--L 333

Query: 970  SSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCKIIEKSINDFYK--- 1140
              NQKLGL  ALL  G+W  AQ ++D++P +YA  +   +  ALC+++  ++   Y+
Sbjct: 334  PDNQKLGLLEALLRLGDWHHAQSIMDQMPSFYAT-SHKAIALALCQLVHLTVEPLYRRVG 392

Query: 1141 --KNCSLNLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLS-SVLAYLGPRIAFRASTNI 1311
              K      F  L     P         +P E++EDL + + S+L YLGP ++
Sbjct: 393  LPKGARGRPFHPLKSKGAP---------QPTENFEDLRRDTFSMLGYLGPHLSNDPVLIA 443

Query: 1312 KIVRLLTAYYRXXXXXXXXXXXXXNQNFVEVVSECLLPSLTLSETNVALSEEIWQLLELF 1491
            KI RL  A+ +                F+ +  + LLPSL+L E+N  +SEE+W L +LF
Sbjct: 444  KIARLGKAFMKEDTLLSC---------FLSIADQVLLPSLSLMESNACMSEELWGLFKLF 494

Query: 1492 PYSWRYWMYSKWNLETS-RHPEMHIMKGKIHGRTKYVLKRLSKETVKMMGRQLGKLCHIH 1668
            PY  RY +Y +W  ET   HP +  +K +   R +Y++KRL+KE VK  GRQ+GKL H +
Sbjct: 495  PYQHRYRLYGQWKNETYLSHPLLVKVKAQTVERARYIMKRLTKENVKQSGRQVGKLSHSN 554

Query: 1669 PSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTY-----CIISQLADPSKQALKS 1833
            P+ +  Y+LSQ+Q +DNFI PVVDSL+YLTSL +D+L       CII  LA+P K+ +K
Sbjct: 555  PTILFDYMLSQIQWYDNFIVPVVDSLKYLTSLSYDILACILQMDCIIEALANPQKEKMKH 614

Query: 1834 TDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIE 2013
             D TIS WLQ+L +L G+++R+Y +EL G+L YV NQLK  KS+D+L+L+E++Q M+ IE
Sbjct: 615  DDTTISSWLQSLASLCGAVFRKYSIELAGLLQYVTNQLKTGKSFDLLILKEVVQKMAGIE 674

Query: 2014 SISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQK 2193
              +  T EQ+EA+ GG+ LK E   +      +K++QRL++ L++ +LA+ L + +AQ +
Sbjct: 675  ITAEMTSEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKEVLVEHELALPLCLLMAQHR 734

Query: 2194 EHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLG 2373
              +V+ E     LKLVG + DQC DT  Q   FL+  L  +D+ K VP++  L + +
Sbjct: 735  NGVVFLEGGEKHLKLVGHLYDQCHDTLVQFGGFLASNLSTEDYIKLVPSIDVLCNQFHTP 794

Query: 2374 MEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVEMLM 2553
             +A   L+RP++  +I   YD  KK      E G K     QQK   + +A E  ++ +
Sbjct: 795  HDAAFFLSRPMYAHQILSKYDELKK-----AEKGNK----QQQKNHKYVAACEQVMKPVH 845

Query: 2554 DELKASEPG-MEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSREDSHG----- 2715
            + + +  P  + +++  +F+A FW LTMYD+ VP AAYER ++ LK Q RE
Sbjct: 846  ESVVSLHPARVWDDLRPQFYATFWSLTMYDLAVPHAAYEREINKLKAQIREIEENAEMPM 905

Query: 2716 KAKKTDKQ----LESKLREEQKRQIEHVERCKVWLLNKKDS-LIDEQFHNSVLEALIQQC 2880
              KK +K+    L+ KL+EE+K+Q EHV+R    L  +KD+ L+ +   N  +   +Q C
Sbjct: 906  NKKKKEKERCTALQEKLQEEEKKQTEHVQRVLYRLKLEKDNWLLTKSTKNETITKFLQLC 965

Query: 2881 LLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLAC 3060
            L PR IFS +DAV+C  F  ++H+ +TP F ++L  DR+F  II  +A  TENE++
Sbjct: 966  LFPRCIFSSIDAVYCAHFVELVHQQKTPNFCTLLCYDRVFSAIIYTVASCTENESHRYGR 1025

Query: 3061 FFEILLCTVQRWHSEKEVFEKECAGFPGMIT------------KQAIEYQTFRKLCYRWQ 3204
            F   +L TV RWHS++  +EKEC  +PG +T               ++Y+ FR + ++W
Sbjct: 1026 FLCCMLETVTRWHSDRATYEKECVSYPGFLTVFRATHLEGGNKADQLDYENFRHVVHKWH 1085

Query: 3205 IRFTAMFKTVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKR 3384
               T    +V   +  DY  IRN LI++TK+   +P + +    +E  V K+  +EK +R
Sbjct: 1086 YMLTK--ASVHCLETGDYTHIRNILIVLTKILPFYPKVLNLGQALECRVHKICLKEKEQR 1143

Query: 3385 DDLSLKAASYVGKLKMRTVKIYAQN 3459
             DL + A  Y G+LK + V +  +N
Sbjct: 1144 PDLYVLAIGYSGRLKSQKVHMVPEN 1168


>gi|37546516|ref|XP_047325.4| Tho2 [Homo sapiens]
          Length = 1593

 Score =  668 bits (1724), Expect = 0.0
 Identities = 428/1304 (32%), Positives = 679/1304 (51%), Gaps = 62/1304 (4%)
 Frame = +1

Query: 103  RDAISSELIDVLVLTEPESEFADNASTSKENFESFV----NLLTNTIIPEEILRLELDCF 270
            R+ + S L DV  + + E+   +  S  ++ F   V     L+++T++ E +    L+
Sbjct: 77   REDMPSILADVFCILDIETNCLEEKS-KRDYFTQLVLACLYLVSDTVLKERLDPETLESL 135

Query: 271  ----KKDDHSKALIRLKTKVYFKQAKFNLFREESEGYSKLVTELMXXXXXXXXXXXXXKI 438
                +    ++  +++KTK+++KQ KFNL REE+EGY+KL+ EL               +
Sbjct: 136  GLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAEL----GQDLSGSITSDL 191

Query: 439  LKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEIDVVRD--YLCALLGFK 612
            +   + SLIG FNLDPNRV DVILEVFE  P     FI+LL+    + +   LC +LGFK
Sbjct: 192  ILENIKSLIGCFNLDPNRVLDVILEVFECRPEHDDFFISLLESYMSMCEPQTLCHILGFK 251

Query: 613  FTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAIKEGHRSRMQNAQERA 792
            F FYQ +   +TP SLY + A L+Q  +ID+  +  +++P    I + H+      +E A
Sbjct: 252  FKFYQ-EPNGETPSSLYRVAAVLLQFNLIDLDDLYVHLLPADNCIMDEHK------REIA 304

Query: 793  SKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDEDIKLSEGFNEEYVLS 972
               + +   +M ++ S   DE                  + +E E+ K+ +
Sbjct: 305  EAKQIVRKLTMVVLSSEKMDERE----------------KEKEKEEEKVEKP-------P 341

Query: 973  SNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCKIIEKSINDFYKKNCS 1152
             NQKLGL  ALL+ G+W+ AQ ++D++P YYA  +   +  A+CK+I  +I   Y++
Sbjct: 342  DNQKLGLLEALLKIGDWQHAQNIMDQMPPYYAA-SHKLIALAICKLIHITIEPLYRR--- 397

Query: 1153 LNLFGDLIKSTKPVLDDMGNGLRP--IESWEDLGK-LSSVLAYLGPRIAFRASTNIKIVR 1323
                G    +    ++ + N   P   ES+EDL + + ++  YLGP ++       K+VR
Sbjct: 398  ---VGVPKGAKGSPVNALQNKRAPKQAESFEDLRRDVFNMFCYLGPHLSHDPILFAKVVR 454

Query: 1324 LLTAYYRXXXXXXXXXXXXXNQNFV-----EVVSECLLPSLTLSETNVALSEEIWQLLEL 1488
            +  ++ +                 +      +  + LLPSL+L + N  +SEE+W + +
Sbjct: 455  IGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKT 514

Query: 1489 FPYSWRYWMYSKWNLET-SRHPEMHIMKGKIHGRTKYVLKRLSKETVKMMGRQLGKLCHI 1665
            FPY  RY +Y +W  ET + HP +  +K +   R KY++KRL+KE VK  GRQ+GKL H
Sbjct: 515  FPYQHRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHS 574

Query: 1666 HPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQLADPSKQALKSTDAT 1845
            +P+ +  Y+LSQ+Q +DN I PVVDSL+YLTSL +DVL YCII  LA+P K+ +K  D T
Sbjct: 575  NPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTT 634

Query: 1846 ISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMSWIESISG 2025
            IS WLQ+L +  G+++R+YP++L G+L YV NQLK  KS+D+L+L+E++Q M+ IE
Sbjct: 635  ISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEE 694

Query: 2026 ATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVAQQKEHIV 2205
             T EQ+EA+ GG+ LK E   +      +K++QRL+DALL  DLA+ L + +AQQ+  ++
Sbjct: 695  MTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVI 754

Query: 2206 YNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDYSLGMEAT 2385
            + E     LKLVGK+ DQC DT  Q   FL+  L  +D+ KRVP++  L +++    +A
Sbjct: 755  FQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAA 814

Query: 2386 MCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALE---SQVEMLMD 2556
              L+RP++   IS  YD  KK  K + +         Q K   + ++ E   + V   +
Sbjct: 815  FFLSRPMYAHHISSKYDELKKSEKGSKQ---------QHKVHKYITSCEMVMAPVHEAVV 865

Query: 2557 ELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKKQSR-----EDSHGKA 2721
             L  S+  + ++I  +F+A FW LTMYD+ VP  +YER ++ LK Q +     ++
Sbjct: 866  SLHVSK--VWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNK 923

Query: 2722 KKTDKQ----LESKLREEQKRQIEHVERCKVWLLNKKDS-LIDEQFHNSVLEALIQQCLL 2886
            KK +K+    L+ KL EE+K+Q+EHV+R    L  +KD+ L+ +   N  +   +Q C+
Sbjct: 924  KKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIF 983

Query: 2887 PRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENEANSLACFF 3066
            PR IFS +DAV+C +F  ++H+ +TP F ++L  DR+F +II  +A  TENEA+    F
Sbjct: 984  PRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFL 1043

Query: 3067 EILLCTVQRWHSEKEVFEKECAGFPGMIT------------KQAIEYQTFRKLCYRWQIR 3210
              +L TV RWHS++  +EKEC  +PG +T               ++Y+ FR + ++W  +
Sbjct: 1044 CCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHYK 1103

Query: 3211 FTAMFKTVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDREKGKRDD 3390
             T    +V   +  +Y  IRN LI++TK+   +P + +    +E  V K+   EK KR D
Sbjct: 1104 LTK--ASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVHKICQEEKEKRPD 1161

Query: 3391 LSLKAASYVGKLKMRTVKIYAQNSDY--APVPNKKVSXXXXX-----XXXXXXXXXXXXX 3549
            L   A  Y G+LK R   +  +N  +   P P   V+
Sbjct: 1162 LYALAMGYSGQLKSRKSYMIPENEFHHKDPPPRNAVASVQNGPGGGPSSSSIGSASKSDE 1221

Query: 3550 XXXXPVDKK-------IKVDSKKNGTTSSEKVVKDDEVHQNGSETEKKATVDNKERKKRP 3708
                  DK        +K  +K + TT      K +  + N      KA  +N + K +
Sbjct: 1222 SSTEETDKSRERSQCGVKAVNKASSTTP-----KGNSSNGNSGSNSNKAVKENDKEKGKE 1276

Query: 3709 XXXXXXXXXXXXXPTT----EDGEVKTPSPPPAKKTRIVDRLKR 3828
                         P      +DG+ K     P K  +  +  +R
Sbjct: 1277 KEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKER 1320


>gi|41702296|sp|Q8NI27|THO2_HUMAN THO complex subunit 2 (Tho2)
 gi|20799318|gb|AAM28436.1| Tho2 [Homo sapiens]
          Length = 1478

 Score =  665 bits (1715), Expect = 0.0
 Identities = 421/1259 (33%), Positives = 660/1259 (51%), Gaps = 54/1259 (4%)
 Frame = +1

Query: 214  LLTNTIIPEEILRLELDCFKKDDHSKALIRLKTKVYFKQAKFNLFREESEGYSKLVTELM 393
            +L   + PE +  L L    +  + K+ +++KTK+++KQ KFNL REE+EGY+KL+ EL
Sbjct: 7    VLKERLDPETLESLGLIKQSQQFNQKS-VKIKTKLFYKQQKFNLLREENEGYAKLIAEL- 64

Query: 394  XXXXXXXXXXXXXKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEID 573
                          ++   + SLIG FNLDPNRV DVILEVFE  P     FI+LL+
Sbjct: 65   ---GQDLSGSITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEHDDFFISLLESYM 121

Query: 574  VVRD--YLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAI 747
             + +   LC +LGFKF FYQ +   +TP SLY + A L+Q  +ID+  +  +++P    I
Sbjct: 122  SMCEPQTLCHILGFKFKFYQ-EPNGETPSSLYRVAAVLLQFNLIDLDDLYVHLLPADNCI 180

Query: 748  KEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDE 927
             + H+      +E A   + +   +M ++ S   DE                  + +E E
Sbjct: 181  MDEHK------REIAEAKQIVRKLTMVVLSSEKMDERE----------------KEKEKE 218

Query: 928  DIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCK 1107
            + K+ +          NQKLGL  ALL+ G+W+ AQ ++D++P YYA  +   +  A+CK
Sbjct: 219  EEKVEKP-------PDNQKLGLLEALLKIGDWQHAQNIMDQMPPYYAA-SHKLIALAICK 270

Query: 1108 IIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRP--IESWEDLGK-LSSVLAYLG 1278
            +I  +I   Y++       G    +    ++ + N   P   ES+EDL + + ++  YLG
Sbjct: 271  LIHITIEPLYRR------VGVPKGAKGSPVNALQNKRAPKQAESFEDLRRDVFNMFCYLG 324

Query: 1279 PRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFV-----EVVSECLLPSLTLSE 1443
            P ++       K+VR+  ++ +                 +      +  + LLPSL+L +
Sbjct: 325  PHLSHDPILFAKVVRIGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMD 384

Query: 1444 TNVALSEEIWQLLELFPYSWRYWMYSKWNLET-SRHPEMHIMKGKIHGRTKYVLKRLSKE 1620
             N  +SEE+W + + FPY  RY +Y +W  ET + HP +  +K +   R KY++KRL+KE
Sbjct: 385  CNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKE 444

Query: 1621 TVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQ 1800
             VK  GRQ+GKL H +P+ +  Y+LSQ+Q +DN I PVVDSL+YLTSL +DVL YCII
Sbjct: 445  NVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEA 504

Query: 1801 LADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLL 1980
            LA+P K+ +K  D TIS WLQ+L +  G+++R+YP++L G+L YV NQLK  KS+D+L+L
Sbjct: 505  LANPEKERMKHDDTTISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLIL 564

Query: 1981 REIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLA 2160
            +E++Q M+ IE     T EQ+EA+ GG+ LK E   +      +K++QRL+DALL  DLA
Sbjct: 565  KEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLA 624

Query: 2161 VGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPT 2340
            + L + +AQQ+  +++ E     LKLVGK+ DQC DT  Q   FL+  L  +D+ KRVP+
Sbjct: 625  LPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPS 684

Query: 2341 VRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFT 2520
            +  L +++    +A   L+RP++   IS  YD  KK  K + +         Q K   +
Sbjct: 685  IDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQ---------QHKVHKYI 735

Query: 2521 SALE---SQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKK 2691
            ++ E   + V   +  L  S+  + ++I  +F+A FW LTMYD+ VP  +YER ++ LK
Sbjct: 736  TSCEMVMAPVHEAVVSLHVSK--VWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKV 793

Query: 2692 QSR-----EDSHGKAKKTDKQ----LESKLREEQKRQIEHVERCKVWLLNKKDS-LIDEQ 2841
            Q +     ++     KK +K+    L+ KL EE+K+Q+EHV+R    L  +KD+ L+ +
Sbjct: 794  QMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKS 853

Query: 2842 FHNSVLEALIQQCLLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLI 3021
              N  +   +Q C+ PR IFS +DAV+C +F  ++H+ +TP F ++L  DR+F +II  +
Sbjct: 854  TKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTV 913

Query: 3022 AGLTENEANSLACFFEILLCTVQRWHSEKEVFEKECAGFPGMIT------------KQAI 3165
            A  TENEA+    F   +L TV RWHS++  +EKEC  +PG +T               +
Sbjct: 914  ASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNKADQL 973

Query: 3166 EYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMET 3345
            +Y+ FR + ++W  + T    +V   +  +Y  IRN LI++TK+   +P + +    +E
Sbjct: 974  DYENFRHVVHKWHYKLTK--ASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALER 1031

Query: 3346 AVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQNSDY--APVPNKKVSXXXXX--- 3510
             V K+   EK KR DL   A  Y G+LK R   +  +N  +   P P   V+
Sbjct: 1032 RVHKICQEEKEKRPDLYALAMGYSGQLKSRKSYMIPENEFHHKDPPPRNAVASVQNGPGG 1091

Query: 3511 --XXXXXXXXXXXXXXXXXPVDKK-------IKVDSKKNGTTSSEKVVKDDEVHQNGSET 3663
                                 DK        +K  +K + TT      K +  + N
Sbjct: 1092 GPSSSSIGSASKSDESSTEETDKSRERSQCGVKAVNKASSTTP-----KGNSSNGNSGSN 1146

Query: 3664 EKKATVDNKERKKRPXXXXXXXXXXXXXPTT----EDGEVKTPSPPPAKKTRIVDRLKR 3828
              KA  +N + K +              P      +DG+ K     P K  +  +  +R
Sbjct: 1147 SNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDEKARETKER 1205


>gi|34876073|ref|XP_223180.2| similar to Tho2 [Rattus norvegicus]
          Length = 1785

 Score =  661 bits (1706), Expect = 0.0
 Identities = 407/1192 (34%), Positives = 648/1192 (54%), Gaps = 43/1192 (3%)
 Frame = +1

Query: 13   ETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNASTSKE 192
            + L +L   ++   + P +A   +    + R+ I   L D+  + + E+   +  S  ++
Sbjct: 245  QALYELSYHVIKGTLKPEQASSVLNDISEFREDIPFILADIFCILDIETNCLEEKS-KRD 303

Query: 193  NFESFV----NLLTNTIIPEEILRLELDCF----KKDDHSKALIRLKTKVYFKQAKFNLF 348
            +F   +     L+++T++ E +    L+      +    ++  +++KTK+++KQ KFNL
Sbjct: 304  HFTQLILACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLL 363

Query: 349  REESEGYSKLVTELMXXXXXXXXXXXXXKILKHRVLSLIGQFNLDPNRVTDVILEVFENF 528
            REE+EGY+KL+ EL              +ILK    SLIG FNLDPNRV D+ILEVFE
Sbjct: 364  REENEGYAKLIVELGQDLSGSITSDLILEILK----SLIGCFNLDPNRVLDIILEVFECR 419

Query: 529  PRQKLLFIALLKEIDVVRD--YLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMID 702
            P     FI+LL+    + +   LC +LGFKF FYQ +   +TP SLY   A L+Q  ++D
Sbjct: 420  PEHHDFFISLLQAYMSMCEPQTLCHILGFKFKFYQ-EPNGETPSSLYRAAAVLLQFNLLD 478

Query: 703  MMKILGYMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATT 882
            +  +  +++P    I   ++  +  A++   K       +M ++ S   DE
Sbjct: 479  LDDLYVHLLPADSCIMNEYKREIVEAKQIVKKL------TMVVLPSEKSDER-------- 524

Query: 883  QTISFTTVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEY 1062
                     + ++ +D K+ +          NQKLGL  ALL  G+W+ AQ ++DR+P Y
Sbjct: 525  ---------EKEKKKDDKVEKA-------PDNQKLGLLEALLIIGDWQHAQSIMDRMPPY 568

Query: 1063 YAVQASPRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRP--IESW 1236
            YA      +  A+C +I  +I   Y++       G    +    +  + N   P   ES+
Sbjct: 569  YATSHKV-IALAICNLIHITIEPIYRR------VGVPKGAKGSPVSALQNKKAPKQAESF 621

Query: 1237 EDLGK-LSSVLAYLGPRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFVE---- 1401
            EDL + + S+  YLGP ++       K+VR+  ++ +              +  +
Sbjct: 622  EDLRRDVFSMFCYLGPHLSHDPILFAKVVRIGKSFMKEFQSDGKQENKEKMETILSCLLS 681

Query: 1402 VVSECLLPSLTLSETNVALSEEIWQLLELFPYSWRYWMYSKWNLET-SRHPEMHIMKGKI 1578
            V  + LLPSL+L + N  +SEE+W + + FPY  RY +Y +W  ET + HP +  +K
Sbjct: 682  VTDQVLLPSLSLMDCNACMSEELWAMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAHT 741

Query: 1579 HGRTKYVLKRLSKETVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLT 1758
              R KY++KRL+KE VK  GRQ+GKL H +P+ +  Y+LSQ+Q +DN I PVVDSL+YLT
Sbjct: 742  IDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLT 801

Query: 1759 SLEFDVLTYCIISQLADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVL 1938
            +L +DVL YCII  LA+P K+ +K  D TIS WLQ+L +  G+++R+YP++L G+L YV
Sbjct: 802  ALNYDVLAYCIIEALANPEKERMKHDDTTISNWLQSLASFCGAVFRKYPIDLAGLLQYVA 861

Query: 1939 NQLKLCKSYDMLLLREIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKA 2118
            NQLK  KS+D+L+L+E++Q M+ IE     T EQ+EA+ GG+ LK E   +      +K+
Sbjct: 862  NQLKAGKSFDLLILKEVVQKMAGIEVTEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKS 921

Query: 2119 AQRLRDALLKGDLAVGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLS 2298
            +QRL+DALL  DLA+ L + +AQQ+  +++ E     LKLVGK+ DQC DT  Q   FL+
Sbjct: 922  SQRLKDALLDHDLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLA 981

Query: 2299 VYLKNDDFSKRVPTVRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQ 2478
              L  DD+ KRVP++  L +++    +A   L+RP++   IS  YD  KK  K + +
Sbjct: 982  SNLSTDDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQ--- 1038

Query: 2479 KTRLDTQQKTEMFTSALE---SQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMYDIEV 2649
                  Q K   + ++ E   + V   +  L  S+  + E+I  +F+  FW LTMYD+ V
Sbjct: 1039 ------QHKVHKYITSCEMVMAPVHEAVVSLHISK--VWEDISPQFYTTFWSLTMYDLAV 1090

Query: 2650 PTAAYERTLDALKKQSR-----EDSHGKAKKTDKQ----LESKLREEQKRQIEHVERCKV 2802
            P  +YER ++ LK Q +     ++     KK +K+    L+ KL EE+K+Q+EHV+R
Sbjct: 1091 PHTSYEREVNKLKIQMKAVDDNQEMPLNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLH 1150

Query: 2803 WLLNKKDS-LIDEQFHNSVLEALIQQCLLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSV 2979
             L  +KD+ L+ +   N  +   +Q C+ PR IFS +D+V+C  F  ++H+ +TP F ++
Sbjct: 1151 RLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAIDSVYCAHFVELVHQQKTPNFSTL 1210

Query: 2980 LIIDRLFENIIPLIAGLTENEANSLACFFEILLCTVQRWHSEKEVFEKECAGFPGMIT-- 3153
            L  DR+F +II ++A  TENEA+    F   +L TV RWHS++  +EKEC  +PG +T
Sbjct: 1211 LCYDRVFSDIIYMVASFTENEASRYGRFLCCMLETVTRWHSDRSTYEKECGNYPGFLTIL 1270

Query: 3154 ----------KQAIEYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIMMTKLTS 3303
                         ++Y+ FR + ++W  + T    +V   +  +Y  IRN LI++TK+
Sbjct: 1271 RATGFDGGNKADQLDYENFRHVVHKWHYKLTK--ASVHCLETGEYTHIRNILIVLTKILP 1328

Query: 3304 GFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQN 3459
             +P + +    +E  V K+   EK K+ DL   A  Y G+LK R   +  +N
Sbjct: 1329 WYPKVLNLGQALERRVHKICQEEKEKKPDLYALAMVYSGQLKSRKSYMIPEN 1380


>gi|38080348|ref|XP_144450.2| similar to Tho2 [Mus musculus]
          Length = 1589

 Score =  656 bits (1693), Expect = 0.0
 Identities = 411/1196 (34%), Positives = 648/1196 (53%), Gaps = 47/1196 (3%)
 Frame = +1

Query: 13   ETLTQLCLDIVHMKITPMKAYERILTEKKDRDAISSELIDVLVLTEPESEFADNASTSKE 192
            + L +L   ++   + P +A   +    + R+ I   L D+  + + E+   +  S  ++
Sbjct: 49   QALYELSYHVIKGTLKPEQASNVLNDISEFREDIPFILADIFCILDIETNCLEEKS-KRD 107

Query: 193  NFESFV----NLLTNTIIPEEILRLELDCF----KKDDHSKALIRLKTKVYFKQAKFNLF 348
            +F   +     L+++T++ E +    L       +    ++  +++KTK+++KQ KFNL
Sbjct: 108  HFTQLILACLYLVSDTVLKERLDPETLGSLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLL 167

Query: 349  REESEGYSKLVTELMXXXXXXXXXXXXXKILKHRVLSLIGQFNLDPNRVTDVILEVFENF 528
            REE+EGY+KL+ EL              +ILK    SLIG FNLDPNRV D+ILEVFE
Sbjct: 168  REENEGYAKLIVELGQDLSGNITSDLILEILK----SLIGCFNLDPNRVLDIILEVFECR 223

Query: 529  PRQKLLFIALLKEIDVVRD--YLCALLGFKFTFYQSDKKKKTPYSLYVLTASLIQHEMID 702
            P     FI+LL+    + +   LC +LGFKF FYQ +   +TP SLY   A L+Q  +ID
Sbjct: 224  PEHHDFFISLLEAYMSMCEPHTLCHILGFKFKFYQ-EPNGETPSSLYRAAAVLLQFNLID 282

Query: 703  MMKILGYMIPKAEAIKEGHRSRMQNAQERASKAETISTASMPIMDSRGFDENGIGGNATT 882
            +  +  +++P    I   ++  +  A++   K       +M ++ S   DE
Sbjct: 283  LDDLYVHLLPADSCIVSEYKREIVEAKQIVKKL------TMVVLPSEKSDER-------- 328

Query: 883  QTISFTTVIQLQEDEDIKLSEGFNEEYVLSSNQKLGLTCALLESGNWKQAQMLIDRLPEY 1062
                     + ++ +D K+ +          NQKLGL  ALL  G+WK AQ ++D +P Y
Sbjct: 329  ---------EKEKKKDDKVEKA-------PDNQKLGLLEALLIIGDWKHAQSIMDHMPPY 372

Query: 1063 YAVQASPRLCRALCKIIEKSINDFYKKNCSLNLFGDLIKSTKPVLDDMGNGLRP--IESW 1236
            YA      +  A+C +I  +I   Y++       G    +    ++ + N   P   ES+
Sbjct: 373  YATSHKV-IALAICNLIHITIEPIYRR------VGVPKGAKGSPVNALQNKKAPKQAESF 425

Query: 1237 EDLGK-LSSVLAYLGPRIAFRASTNIKIVRLLTAYYRXXXXXXXXXXXXXNQNFVEVVSE 1413
            EDL + + S+  YLGP ++       K+VR+  ++ +             N+  +E +
Sbjct: 426  EDLRRDVFSMFYYLGPHLSHDPILFAKVVRIGKSFMKEFQSDGKQE----NKEKMEAILS 481

Query: 1414 CLL--------PSLTLSETNVALSEEIWQLLELFPYSWRYWMYSKWNLET-SRHPEMHIM 1566
            CLL        PSL+L + N  +SEE+W + + FPY  RY +Y +W  ET + HP +  +
Sbjct: 482  CLLSVTDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNSHPLLVKV 541

Query: 1567 KGKIHGRTKYVLKRLSKETVKMMGRQLGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSL 1746
            K     R KY++KRL+KE VK  GRQ+GKL H +P+ +  Y+LSQ+Q +DN I PVVDSL
Sbjct: 542  KAYTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSL 601

Query: 1747 RYLTSLEFDVLTYCIISQLADPSKQALKSTDATISPWLQALGTLVGSLYRRYPLELNGML 1926
            +YLT+L +DVL YCII  LA+P K+ +K  D TIS WLQ+L +  G+++R+YP++L G+L
Sbjct: 602  KYLTALNYDVLAYCIIEALANPEKERMKHDDTTISNWLQSLASFCGAVFRKYPIDLAGLL 661

Query: 1927 DYVLNQLKLCKSYDMLLLREIIQNMSWIESISGATKEQIEALGGGDLLKQEADGYSTATK 2106
             YV NQLK  KS+D+L+L+E++Q M+ IE     T EQ+EA+ GG+ LK E   +
Sbjct: 662  QYVANQLKAGKSFDLLILKEVVQKMAGIEVTEEMTMEQLEAMTGGEQLKAEGGYFGQIRN 721

Query: 2107 NRKAAQRLRDALLKGDLAVGLAISVAQQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLV 2286
             +K++QRL+DALL  DLA+ L + +AQQ+  +++ E     LKLVGK+ DQC DT  Q
Sbjct: 722  TKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFG 781

Query: 2287 SFLSVYLKNDDFSKRVPTVRELLSDYSLGMEATMCLARPIFFSRISDHYDAAKKISKAAV 2466
             FL+  L  DD+ KRVP++  L +++    +A   L+RP++   IS  YD  KK  K +
Sbjct: 782  GFLASNLSTDDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSK 841

Query: 2467 EDGQKTRLDTQQKTEMFTSALE---SQVEMLMDELKASEPGMEENIPVKFFAVFWMLTMY 2637
            +         Q K   +  + E   + V   +  L  S+  + ++I  +F+  FW LTMY
Sbjct: 842  Q---------QHKVHKYIMSCEMVMAPVHEAVVSLHISK--VWDDISPQFYTTFWSLTMY 890

Query: 2638 DIEVPTAAYERTLDALKKQSR--EDSHG---KAKKTDKQ----LESKLREEQKRQIEHVE 2790
            D+ VP  +YER ++ LK Q +  +DS       KK +K+    L+ KL EE+K+Q EHV+
Sbjct: 891  DLAVPHTSYEREVNKLKIQMKAVDDSQEMPLNKKKKEKERCTALQDKLLEEEKKQTEHVQ 950

Query: 2791 RCKVWLLNKKDS-LIDEQFHNSVLEALIQQCLLPRAIFSELDAVFCGQFFMMLHEMRTPF 2967
            R    L  +KD+ L+ +   N  +   +Q C+ PR IFS +D+V+C  F  ++H+ +TP
Sbjct: 951  RVLHRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAIDSVYCAHFVELVHQQKTPN 1010

Query: 2968 FPSVLIIDRLFENIIPLIAGLTENEANSLACFFEILLCTVQRWHSEKEVFEKECAGFPGM 3147
            F ++L  DR+F +II ++A  TENEA+    F   +L TV RWHS++  +EKEC  +PG
Sbjct: 1011 FSTLLCYDRVFSDIIYMVASFTENEASRYGRFLCCMLETVTRWHSDRSTYEKECGNYPGF 1070

Query: 3148 IT------------KQAIEYQTFRKLCYRWQIRFTAMFKTVFTKDDADYVLIRNSLIMMT 3291
            +T               ++Y+ FR + ++W  + T    +V   +  +Y  IRN LI++T
Sbjct: 1071 LTILRATGFDGGNKADQLDYENFRHVVHKWHYKLTK--ASVHCLETGEYTHIRNILIVLT 1128

Query: 3292 KLTSGFPVISHAVATMETAVTKLKDREKGKRDDLSLKAASYVGKLKMRTVKIYAQN 3459
            K+   +P + +    +E  V K+   EK K+ DL   A  Y G+LK R   +  +N
Sbjct: 1129 KILPWYPKVLNLGQALERRVHKICQEEKEKKPDLYALAMVYSGQLKSRKSYMIPEN 1184


>gi|31222868|ref|XP_317233.1| ENSANGP00000011945 [Anopheles gambiae]
 gi|21300223|gb|EAA12368.1| ENSANGP00000011945 [Anopheles gambiae str.
            PEST]
          Length = 1606

 Score =  637 bits (1643), Expect = 0.0
 Identities = 404/1179 (34%), Positives = 637/1179 (53%), Gaps = 54/1179 (4%)
 Frame = +1

Query: 112  ISSELIDVLVLTEPESEFA---DNASTSKE--NFESFVNLLTNTIIPEEIL--RLELDCF 270
            + S L+DV  + + E+  A   D A  S+E  NF  ++   +   + E++L  RLE+D
Sbjct: 102  VPSILLDVFGIFDAETATAGSGDGAPPSEERTNF-CYIAKESERFVSEKLLKERLEIDTL 160

Query: 271  ------KKDDHSKALIRLKTKVYFKQAKFNLFREESEGYSKLVTEL-MXXXXXXXXXXXX 429
                  K        I++KTK+Y+KQ +FNLFREESEGY+KL+TEL
Sbjct: 161  QDVGTIKNRSFYTRFIKVKTKLYYKQRRFNLFREESEGYAKLMTELNQEFNQETMTVQNV 220

Query: 430  XKILKHRVLSLIGQFNLDPNRVTDVILEVFENFPRQKLLFIALLKEIDVVRDYLCALLGF 609
             +I+K    SLIG FNLDPNRV D+ILE FE  P Q  +FI LL+      + +C +LG+
Sbjct: 221  LEIIK----SLIGCFNLDPNRVLDIILESFEARPEQDRIFIPLLQAYINDGNIICEVLGY 276

Query: 610  KFTFYQSDKKKKTPYSLYVLTASLIQHEMIDMMKILGYMIPKAEAIKEGHRSRMQNAQER 789
            K+ ++      +TP SL+ +TA L+QH +I +  I  ++ P  ++I     + +  A+E
Sbjct: 277  KYRYFAD---AQTPGSLFKVTALLLQHGVIKLDDIYAWLNPPDKSIVADWEAEIAQAKEY 333

Query: 790  ASKAETISTASMPIMDSRGFDENGIGGNATTQTISFTTVIQLQEDEDIKLSEGFNEEYVL 969
              K   I T                                 +E E     E   E+Y L
Sbjct: 334  VRKLNVILTNKD------------------------------KEPEQEPEFETAPEKYAL 363

Query: 970  SSNQKLGLTCALLESGNWKQAQMLIDRLPEYYAVQASPRLCRALCKIIEKSINDFYKKNC 1149
              NQK GL  ALL  G+W  AQ LI +LP+   +   P + RALC+++   I   Y+  C
Sbjct: 364  --NQKWGLCEALLTIGDWNTAQQLIRKLPDQSVMVHEP-IARALCRLLHMIIEPVYRLKC 420

Query: 1150 SL--NLFGDLIKSTKPVLDDMGNGLRPIESWEDLGKLS-SVLAYLGPRIAFRASTNIKIV 1320
            +L  N+ G  I S   VL+ +     P+ S   L   +  +   LGP + + +    K++
Sbjct: 421  ALPANIKGRAI-SMYGVLNKLAPP--PVTSLTKLRLHAFPMFVALGPSLHYDSVLLYKLL 477

Query: 1321 RLLTAYYRXXXXX--------XXXXXXXXNQNFVEVVS---ECLLPSLTLSETNVALSEE 1467
            RL+                           Q + +++S     +LPSL   + N  ++EE
Sbjct: 478  RLMRVILTDMNVDPLNPPSPGAGSTLTEHEQLYYDILSLLDAAVLPSLAYMDCNCCVAEE 537

Query: 1468 IWQLLELFPYSWRYWMYSKWNLETSR-HPEMHIMKGKIHGRTKYVLKRLSKETVKMMGRQ 1644
            IW +++L+PY +RY +Y++W  +T +  P++   +G    + K ++KR+SKE  K +GR
Sbjct: 538  IWSIVKLYPYQYRYSLYARWKNDTFQLQPQLIHRRGTAQKQIKALMKRVSKENSKPVGRL 597

Query: 1645 LGKLCHIHPSTVLSYLLSQVQTFDNFIGPVVDSLRYLTSLEFDVLTYCIISQLADPSKQA 1824
            +GKL H  P  +  Y+L Q+Q +DN I PVVDSL+YLTSL +DVL YC+I  L    +
Sbjct: 598  IGKLSHCSPGFLFEYILLQIQIYDNLIAPVVDSLKYLTSLSYDVLGYCLIEALEQVDRNP 657

Query: 1825 LKSTDATISPWLQALGTLVGSLYRRYPLELNGMLDYVLNQLKLCKSYDMLLLREIIQNMS 2004
            +++   +IS WLQ+L    G++Y++Y +EL+G+L YV NQLK  KS D+L+L+E++Q M+
Sbjct: 658  MQNDGTSISLWLQSLANFCGAIYKKYNIELSGLLQYVANQLKSHKSLDLLILKEVVQKMA 717

Query: 2005 WIESISGATKEQIEALGGGDLLKQEADGYSTATKNRKAAQRLRDALLKGDLAVGLAISVA 2184
             IE+    T EQ++A+ GG+LL+ EA  +S     +K++QRL++AL   DLAV L + +A
Sbjct: 718  GIEAAEEMTNEQLQAMCGGELLRGEAGYFSQVRNTKKSSQRLKEALASNDLAVALCLLIA 777

Query: 2185 QQKEHIVYNESSTLPLKLVGKMVDQCSDTFQQLVSFLSVYLKNDDFSKRVPTVRELLSDY 2364
            QQK  ++Y E++   LKLVGK+ DQC DT  Q  +FL      +++ +R+PT+  +L  Y
Sbjct: 778  QQKHCVIYRETAQSHLKLVGKLYDQCQDTLVQFGTFLGSTYSVEEYVERLPTIHNMLQKY 837

Query: 2365 SLGMEATMCLARPIFFSRISDHYDAAKKISKAAVEDGQKTRLDTQQKTEMFTSALESQVE 2544
             +  +    LARP+F   I+  YD  +K    A  +G+K  L T QK   +  A    +
Sbjct: 838  HIHSDVAFFLARPMFSHAINQKYDQLRK----AEPNGKK--LSTSQKMAKYLEATAHVMN 891

Query: 2545 MLMDELK-ASEPGMEENIPVKFFAVFWMLTMYDIEVPTAAYERTLDALKK------QSRE 2703
             +++ ++    P + E+I  +F   FW L+MYD++VP  +Y+R +  LK+      +S+E
Sbjct: 892  PVIESVRPLHPPKIWEDISPQFLVSFWSLSMYDLQVPMESYQREISKLKQLSMAVMESKE 951

Query: 2704 DSHGKAKKTDKQ---LESKLREEQKRQIEHVERCKVWLLNKKD----SLIDEQFHNSVLE 2862
             +  K KK  ++   L  KL++E+K+Q EHV++    L N+KD    S   +   N  +
Sbjct: 952  QNASKNKKEQERYVALMDKLQDERKKQQEHVDKIMHRLTNEKDYWFLSRSAKSAKNETIT 1011

Query: 2863 ALIQQCLLPRAIFSELDAVFCGQFFMMLHEMRTPFFPSVLIIDRLFENIIPLIAGLTENE 3042
              +Q CL PR  F+ LDA++C +F   +H ++T  F ++L  DR+F +I   +   TENE
Sbjct: 1012 QFLQLCLFPRCTFTALDAIYCAKFVHTIHNLKTANFSTLLCYDRIFCDITYSVTSCTENE 1071

Query: 3043 ANSLACFFEILLCTVQRWHSEKEVFEKECAGFPGMITK-----------QAIEYQTFRKL 3189
            A     F   +L TV RWHS++  F KECA +PG +TK             + Y+ +R +
Sbjct: 1072 ATRYGRFLCAMLETVMRWHSDEATFNKECANYPGFVTKFRVSNQYSEAIDHVNYENYRHV 1131

Query: 3190 CYRWQIRFTAMFKTVFTKDDADYVLIRNSLIMMTKLTSGFPVISHAVATMETAVTKLKDR 3369
            C++W  + T     VF  D  DY+ IRNSLI++ ++   FPV++     +E  V K+++
Sbjct: 1132 CHKWHYKITKAM--VFCLDSKDYMQIRNSLIILMRILPHFPVLTKLSQILEKKVEKVREE 1189

Query: 3370 EKGKRDDLSLKAASYVGKLKMRTVKIYAQNSDYAPVPNK 3486
            EK +R DL + A+SY+G+LK +  ++  + SD+  VP K
Sbjct: 1190 EKNQRQDLFVLASSYIGQLKAKASQMMLE-SDFHQVPEK 1227




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